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Ascendis Pharma A/S

244 hedge funds and large institutions have $10.1B invested in Ascendis Pharma A/S in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 77 increasing their positions, 88 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

125% more first-time investments, than exits

New positions opened: 54 | Existing positions closed: 24

16% more capital invested

Capital invested by funds: $8.78B → $10.1B (+$1.37B)

14% more funds holding

Funds holding: 214244 (+30)

1.54% more ownership

Funds ownership: 105.86%107.4% (+1.5%)

0% more funds holding in top 10

Funds holding in top 10: 1414 (0)

13% less repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 88

38% less call options, than puts

Call options by funds: $23.8M | Put options by funds: $38.3M

Holders
244
Holders Change
+30
Holders Change %
+14.02%
% of All Funds
3.27%
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.19%
New
54
Increased
77
Reduced
88
Closed
24
Calls
$23.8M
Puts
$38.3M
Net Calls
-$14.5M
Net Calls Change
+$6.32M
Name Holding Trade Value Shares
Change
Change in
Stake
GPP
76
Great Point Partners
Connecticut
$7.79M +$7.14M +50,000 New
Jane Street
77
Jane Street
New York
$7.53M +$1.85M +12,969 +37%
DT
78
Diversified Trust
Tennessee
$7.25M +$216K +1,510 +3%
Neuberger Berman Group
79
Neuberger Berman Group
New York
$7.22M +$1.17M +8,201 +22%
TI
80
Trexquant Investment
Connecticut
$6.82M +$2.38M +16,693 +62%
Lazard Asset Management
81
Lazard Asset Management
New York
$6.72M +$6.16M +43,123 New
Alyeska Investment Group
82
Alyeska Investment Group
Illinois
$6.61M -$16.1M -112,584 -73%
ZP
83
Zimmer Partners
New York
$5.63M -$8.68M -60,800 -63%
ACM
84
Atika Capital Management
New York
$5.49M +$5.03M +35,200 New
TLP
85
Tri Locum Partners
New York
$5.04M +$4.62M +32,325 New
Royal Bank of Canada
86
Royal Bank of Canada
Ontario, Canada
$5.01M -$29.7K -208 -0.6%
ACM
87
Aquatic Capital Management
Illinois
$4.76M +$4.12M +28,836 +1,723%
MC
88
Matisse Capital
Oregon
$4.62M -$117K -822 -3%
DekaBank Deutsche Girozentrale
89
DekaBank Deutsche Girozentrale
Germany
$4.57M
Deutsche Bank
90
Deutsche Bank
Germany
$4.47M -$819K -5,734 -17%
CM
91
Caption Management
Oklahoma
$4.05M -$2.77M -19,381 -43%
Brown Advisory
92
Brown Advisory
Maryland
$4.03M -$1.49M -10,426 -29%
CIS
93
Capital International Sarl
California
$3.96M +$225K +1,576 +7%
Wells Fargo
94
Wells Fargo
California
$3.75M +$776K +5,433 +29%
Russell Investments Group
95
Russell Investments Group
United Kingdom
$3.7M +$2.93M +20,532 +639%
ACP
96
Acuta Capital Partners
California
$3.64M +$52K +364 +2%
Marshall Wace
97
Marshall Wace
United Kingdom
$3.47M -$13.1M -91,951 -80%
Nomura Asset Management
98
Nomura Asset Management
Japan
$3.32M +$114K +796 +4%
Tudor Investment Corp
99
Tudor Investment Corp
Connecticut
$3.32M +$3.04M +21,299 New
Citigroup
100
Citigroup
New York
$3.3M +$16.6K +116 +0.6%

ASND Hedge Fund Activity: Q1 2025 in Review

244 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q1 2025, worth a combined $10.1B — up 16% from $8.78B a quarter earlier.

Buyers outnumbered sellers: 54 funds opened new ASND positions and 24 closed out — a net gain of 30 holders — while 77 added to existing stakes and 88 trimmed.

The largest buyer was Morgan Stanley, adding an estimated $154M. The largest seller was Camber Capital Management, cutting an estimated $64.3M.

  • 244 institutional investors held Ascendis Pharma A/S (ASND) as of Q1 2025, up from 214 in Q4 2024.
  • Funds reported $10.1B of Ascendis Pharma A/S stock for Q1 2025, up 16% quarter-over-quarter.
  • 54 funds opened new Ascendis Pharma A/S positions in Q1 2025 and 24 closed out, a net change of +30 holders.
  • The largest Ascendis Pharma A/S buyer in Q1 2025 was Morgan Stanley, an estimated $154M added.
  • The largest Ascendis Pharma A/S seller in Q1 2025 was Camber Capital Management, an estimated $64.3M sold.

Based on aggregated 13F filings for Q1 2025.