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Ascendis Pharma A/S

302 hedge funds and large institutions have $13.8B invested in Ascendis Pharma A/S in 2025 Q4 according to their latest regulatory filings, with 62 funds opening new positions, 121 increasing their positions, 91 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

211% more call options, than puts

Call options by funds: $189M | Put options by funds: $60.8M

68% more first-time investments, than exits

New positions opened: 62 | Existing positions closed: 37

33% more repeat investments, than reductions

Existing positions increased: 121 | Existing positions reduced: 91

9% more capital invested

Capital invested by funds: $12.7B → $13.8B (+$1.09B)

8% more funds holding

Funds holding: 279302 (+23)

0.91% more ownership

Funds ownership: 103.53%104.44% (+0.91%)

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
302
Holders Change
+23
Holders Change %
+8.24%
% of All Funds
3.67%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.15%
New
62
Increased
121
Reduced
91
Closed
37
Calls
$189M
Puts
$60.8M
Net Calls
+$128M
Net Calls Change
+$43.4M
Name Holding Trade Value Shares
Change
Change in
Stake
AIP
51
ARS Investment Partners
New York
$37.2M -$218K -1,056 -0.6%
O
52
OrbiMed
New York
$36.7M -$4.12M -19,928 -10%
Bank of America
53
Bank of America
North Carolina
$34.7M +$2.99M +14,491 +10%
DCM
54
Driehaus Capital Management
Illinois
$33.3M -$4.73M -22,896 -13%
RHJA
55
Rice Hall James & Associates
California
$30.9M -$422K -2,044 -1%
FLSM
56
Frazier Life Sciences Management
California
$28.4M
FTM
57
First Turn Management
California
$28.1M -$2.99M -14,483 -10%
OBAM
58
ODDO BHF Asset Management
France
$27.7M +$2.06M +9,958 +8%
D.E. Shaw & Co
59
D.E. Shaw & Co
New York
$26.8M +$25.2M +122,182 +3,407%
MCM
60
Moore Capital Management
New York
$26.7M +$7.23M +35,000 +39%
Lord, Abbett & Co
61
Lord, Abbett & Co
New Jersey
$25.6M -$6.45M -31,230 -21%
CCM
62
Catalio Capital Management
New York
$25.4M -$5.31M -25,689 -18%
BSA
63
Braun Stacey Associates
New York
$25.4M +$5.19M +25,148 +27%
IMC Chicago
64
IMC Chicago
Illinois
$24.2M +$23.5M +113,682 New
Loomis, Sayles & Company
65
Loomis, Sayles & Company
Massachusetts
$23.9M -$8.5M -41,165 -27%
1832 Asset Management
66
1832 Asset Management
Ontario, Canada
$23.5M
WP
67
Woodline Partners
California
$21.8M
CAM
68
Cormorant Asset Management
Massachusetts
$21.3M +$20.7M +100,000 New
IHAM
69
Integral Health Asset Management
New York
$19.2M +$6.2M +30,000 +50%
RCAP
70
Resolute Capital Asset Partners
Colorado
$18.9M -$15.9M -77,045 -47%
DCM
71
Defilade Capital Management
California
$18.3M +$17.7M +85,694 New
ECM
72
ExodusPoint Capital Management
New York
$17.7M +$12M +58,165 +235%
BBL
73
Beck Bode LLC
Massachusetts
$17.3M +$16.7M +81,087 New
Schroder Investment Management Group
74
Schroder Investment Management Group
United Kingdom
$15.6M +$8.24M +39,919 +120%
Pictet Asset Management
75
Pictet Asset Management
Switzerland
$15.5M -$752K -3,640 -5%