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Ascendis Pharma A/S

247 hedge funds and large institutions have $10.9B invested in Ascendis Pharma A/S in 2025 Q2 according to their latest regulatory filings, with 44 funds opening new positions, 82 increasing their positions, 88 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

210% more call options, than puts

Call options by funds: $39.2M | Put options by funds: $12.6M

14% more funds holding in top 10

Funds holding in top 10: 1416 (+2)

10% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 40

7% more capital invested

Capital invested by funds: $10.1B → $10.9B (+$708M)

1% more funds holding

Funds holding: 244247 (+3)

7% less repeat investments, than reductions

Existing positions increased: 82 | Existing positions reduced: 88

4.51% less ownership

Funds ownership: 107.4%102.88% (-4.5%)

Holders
247
Holders Change
+3
Holders Change %
+1.23%
% of All Funds
3.25%
Holding in Top 10
16
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+14.29%
% of All Funds
0.21%
New
44
Increased
82
Reduced
88
Closed
40
Calls
$39.2M
Puts
$12.6M
Net Calls
+$26.6M
Net Calls Change
+$41.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Aberdeen Group
51
Aberdeen Group
United Kingdom
$24.1M -$5.23M -32,125 -19%
FTM
52
First Turn Management
California
$23.2M +$3.49M +21,409 +19%
FLSM
53
Frazier Life Sciences Management
California
$23M
SPPAM
54
Summit Partners Public Asset Management
Massachusetts
$22.4M +$21.2M +130,000 New
MCM
55
Moore Capital Management
New York
$20.7M +$4.89M +30,000 +33%
Bank of New York Mellon
56
Bank of New York Mellon
New York
$20.3M +$4.63M +28,407 +32%
Marshall Wace
57
Marshall Wace
United Kingdom
$20.2M +$15.5M +94,868 +426%
Macquarie Group
58
Macquarie Group
Australia
$20.1M +$19M +116,735 New
RAM
59
Readystate Asset Management
Illinois
$17.4M +$16.4M +100,917 New
Bank of America
60
Bank of America
North Carolina
$16.9M -$6.53M -40,074 -29%
SCM
61
Silverarc Capital Management
Massachusetts
$14.9M +$1.76M +10,801 +14%
Pictet Asset Management
62
Pictet Asset Management
Switzerland
$14.7M -$3.46M -21,220 -20%
SCM
63
Soleus Capital Management
Connecticut
$14.7M +$4.67M +28,700 +51%
UBS Group
64
UBS Group
Switzerland
$14.3M -$14.8M -91,081 -52%
HCA
65
Harbor Capital Advisors
Illinois
$13.6M -$1.21M -7,400 -9%
Millennium Management
66
Millennium Management
New York
$12.6M -$31.3M -191,979 -72%
DCM
67
DAFNA Capital Management
California
$12.5M -$1.26M -7,721 -10%
TI
68
Trexquant Investment
Connecticut
$11.1M +$3.32M +20,375 +47%
OBAM
69
ODDO BHF Asset Management
France
$11M +$10.4M +63,547 New
Ensign Peak Advisors
70
Ensign Peak Advisors
Utah
$10.7M
Geode Capital Management
71
Geode Capital Management
Massachusetts
$10.5M +$481K +2,953 +5%
Manulife (Manufacturers Life Insurance)
72
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$10.1M -$3.4M -20,881 -26%
State Street
73
State Street
Massachusetts
$10M -$1.4M -8,576 -13%
Schroder Investment Management Group
74
Schroder Investment Management Group
United Kingdom
$9.84M -$7.81M -47,928 -46%
SCM
75
Sterling Capital Management
North Carolina
$9.41M +$559K +3,432 +7%

ASND Hedge Fund Activity: Q2 2025 in Review

247 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q2 2025, worth a combined $10.9B — up 7% from $10.1B a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new ASND positions and 40 closed out — a net gain of 4 holders — while 82 added to existing stakes and 88 trimmed.

The largest buyer was Perceptive Advisors, opening a new position worth an estimated $157M. The largest seller was Morgan Stanley, cutting an estimated $269M.

  • 247 institutional investors held Ascendis Pharma A/S (ASND) as of Q2 2025, up from 244 in Q1 2025.
  • Funds reported $10.9B of Ascendis Pharma A/S stock for Q2 2025, up 7% quarter-over-quarter.
  • 44 funds opened new Ascendis Pharma A/S positions in Q2 2025 and 40 closed out, a net change of +4 holders.
  • The largest Ascendis Pharma A/S buyer in Q2 2025 was Perceptive Advisors, an estimated $157M added.
  • The largest Ascendis Pharma A/S seller in Q2 2025 was Morgan Stanley, an estimated $269M sold.

Based on aggregated 13F filings for Q2 2025.