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Ascendis Pharma A/S

244 hedge funds and large institutions have $10.1B invested in Ascendis Pharma A/S in 2025 Q1 according to their latest regulatory filings, with 54 funds opening new positions, 77 increasing their positions, 88 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

125% more first-time investments, than exits

New positions opened: 54 | Existing positions closed: 24

16% more capital invested

Capital invested by funds: $8.78B → $10.1B (+$1.37B)

14% more funds holding

Funds holding: 214244 (+30)

1.54% more ownership

Funds ownership: 105.86%107.4% (+1.5%)

0% more funds holding in top 10

Funds holding in top 10: 1414 (0)

13% less repeat investments, than reductions

Existing positions increased: 77 | Existing positions reduced: 88

38% less call options, than puts

Call options by funds: $23.8M | Put options by funds: $38.3M

Holders
244
Holders Change
+30
Holders Change %
+14.02%
% of All Funds
3.27%
Holding in Top 10
14
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.19%
New
54
Increased
77
Reduced
88
Closed
24
Calls
$23.8M
Puts
$38.3M
Net Calls
-$14.5M
Net Calls Change
+$6.32M
Name Holding Trade Value Shares
Change
Change in
Stake
VPC
51
Vestal Point Capital
New York
$23.4M -$52.8M -369,858 -71%
BNP Paribas Financial Markets
52
BNP Paribas Financial Markets
France
$22.2M +$6.09M +42,601 +43%
Bank of America
53
Bank of America
North Carolina
$21.5M +$15.9M +111,509 +423%
FLSM
54
Frazier Life Sciences Management
California
$20.8M
Victory Capital Management
55
Victory Capital Management
Texas
$19.5M -$918K -6,427 -5%
FTM
56
First Turn Management
California
$17.7M +$3.64M +25,474 +29%
Qube Research & Technologies (QRT)
57
Qube Research & Technologies (QRT)
United Kingdom
$17.1M +$13.8M +96,887 +760%
B
58
Braidwell
Connecticut
$16.6M +$15.2M +106,713 New
Pictet Asset Management
59
Pictet Asset Management
Switzerland
$16.5M -$5.35M -37,441 -26%
Schroder Investment Management Group
60
Schroder Investment Management Group
United Kingdom
$16.2M +$1.74M +12,189 +13%
IHAM
61
Integral Health Asset Management
New York
$15.6M +$14.3M +100,000 New
MCM
62
Moore Capital Management
New York
$14M +$10M +70,000 +350%
Bank of New York Mellon
63
Bank of New York Mellon
New York
$13.9M -$1.31M -9,183 -9%
HCA
64
Harbor Capital Advisors
Illinois
$13.4M +$155K +1,087 +1%
DCM
65
DAFNA Capital Management
California
$12.5M -$3.28M -22,957 -22%
Manulife (Manufacturers Life Insurance)
66
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$12.3M -$546K -3,823 -5%
SCM
67
Silverarc Capital Management
Massachusetts
$11.8M +$3.47M +24,260 +47%
State Street
68
State Street
Massachusetts
$10.4M -$711K -4,977 -7%
FAM
69
Fred Alger Management
New York
$10.1M -$6.72M -47,048 -42%
Ensign Peak Advisors
70
Ensign Peak Advisors
Utah
$9.62M +$8.5M +59,501 +2,677%
SSA
71
Schonfeld Strategic Advisors
New York
$9.41M -$11.2M -78,218 -56%
Geode Capital Management
72
Geode Capital Management
Massachusetts
$9.02M +$111K +774 +1%
EHI
73
Eagle Health Investments
Connecticut
$8.81M +$8.07M +56,500 New
SCM
74
Soleus Capital Management
Connecticut
$8.77M -$12.5M -87,700 -61%
SCM
75
Sterling Capital Management
North Carolina
$7.96M -$825K -5,773 -10%

ASND Hedge Fund Activity: Q1 2025 in Review

244 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q1 2025, worth a combined $10.1B — up 16% from $8.78B a quarter earlier.

Buyers outnumbered sellers: 54 funds opened new ASND positions and 24 closed out — a net gain of 30 holders — while 77 added to existing stakes and 88 trimmed.

The largest buyer was Morgan Stanley, adding an estimated $154M. The largest seller was Camber Capital Management, cutting an estimated $64.3M.

  • 244 institutional investors held Ascendis Pharma A/S (ASND) as of Q1 2025, up from 214 in Q4 2024.
  • Funds reported $10.1B of Ascendis Pharma A/S stock for Q1 2025, up 16% quarter-over-quarter.
  • 54 funds opened new Ascendis Pharma A/S positions in Q1 2025 and 24 closed out, a net change of +30 holders.
  • The largest Ascendis Pharma A/S buyer in Q1 2025 was Morgan Stanley, an estimated $154M added.
  • The largest Ascendis Pharma A/S seller in Q1 2025 was Camber Capital Management, an estimated $64.3M sold.

Based on aggregated 13F filings for Q1 2025.