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Ascendis Pharma A/S

273 hedge funds and large institutions have $14.3B invested in Ascendis Pharma A/S in 2026 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 108 increasing their positions, 106 reducing their positions, and 58 closing their positions.

New
Increased
Maintained
Reduced
Closed

477% more call options, than puts

Call options by funds: $341M | Put options by funds: $59M

33% more funds holding in top 10

Funds holding in top 10: 1216 (+4)

4% more capital invested

Capital invested by funds: $13.8B → $14.3B (+$537M)

2% more repeat investments, than reductions

Existing positions increased: 108 | Existing positions reduced: 106

3.9% less ownership

Funds ownership: 104.44%100.54% (-3.9%)

10% less funds holding

Funds holding: 302273 (-29)

41% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 58

Holders
273
Holders Change
-29
Holders Change %
-9.6%
% of All Funds
3.36%
Holding in Top 10
16
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+33.33%
% of All Funds
0.2%
New
34
Increased
108
Reduced
106
Closed
58
Calls
$341M
Puts
$59M
Net Calls
+$282M
Net Calls Change
+$153M
Name Holding Trade Value Shares
Change
Change in
Stake
Invesco
26
Invesco
Georgia
$82.8M -$50.2M -223,985 -38%
SEI Investments
27
SEI Investments
Pennsylvania
$80.3M +$15.6M +69,673 +25%
BNP Paribas Financial Markets
28
BNP Paribas Financial Markets
France
$70.7M +$468K +2,087 +0.7%
FAM
29
Fred Alger Management
New York
$69.7M -$10.6M -47,213 -13%
AllianceBernstein
30
AllianceBernstein
Tennessee
$59.3M -$2.33M -10,389 -4%
TLP
31
Tri Locum Partners
New York
$58.4M -$2.17M -9,683 -4%
Pictet Asset Management
32
Pictet Asset Management
Switzerland
$56.9M +$40M +178,415 +243%
CS
33
Candriam SCA
Luxembourg
$52.7M +$9.72M +43,338 +23%
Bank of New York Mellon
34
Bank of New York Mellon
New York
$52.3M +$7.64M +34,070 +18%
Two Sigma Investments
35
Two Sigma Investments
New York
$50.4M -$6.18M -27,551 -11%
TD Asset Management
36
TD Asset Management
Ontario, Canada
$49.9M -$3.59M -16,020 -7%
Aberdeen Group
37
Aberdeen Group
United Kingdom
$48.1M -$2.58M -11,523 -5%
AIP
38
ARS Investment Partners
New York
$47.9M +$7.81M +34,845 +20%
UBS Group
39
UBS Group
Switzerland
$47.4M -$22.6M -100,851 -33%
Bank of America
40
Bank of America
North Carolina
$45.4M +$8.07M +36,002 +22%
RSCM
41
Rock Springs Capital Management
Maryland
$44.4M -$2.13M -9,500 -5%
Millennium Management
42
Millennium Management
New York
$43.2M -$16.4M -73,302 -28%
Allspring Global Investments
43
Allspring Global Investments
North Carolina
$42M -$766K -3,418 -2%
O
44
OrbiMed
New York
$41.6M +$2.24M +10,000 +6%
New York State Common Retirement Fund
45
New York State Common Retirement Fund
New York
$39.1M -$2.49M -11,122 -6%
Wells Fargo
46
Wells Fargo
California
$35.3M +$27M +120,419 +356%
PHS
47
PFM Health Sciences
California
$34.8M -$5.75M -25,651 -14%
RHJA
48
Rice Hall James & Associates
California
$33.9M +$749K +3,340 +2%
Lord, Abbett & Co
49
Lord, Abbett & Co
New Jersey
$33.2M +$5.63M +25,120 +21%
Deutsche Bank
50
Deutsche Bank
Germany
$30.9M -$36.2M -161,631 -54%

ASND Hedge Fund Activity: Q1 2026 in Review

273 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Ascendis Pharma A/S (ASND) for Q1 2026, worth a combined $14.3B — up 3.9% from $13.8B a quarter earlier.

Sellers outnumbered buyers: 58 funds closed out of ASND and 34 opened new positions — a net loss of 24 holders — while 106 trimmed existing stakes and 108 added.

The largest buyer was T. Rowe Price Investment Management, adding an estimated $1.01B. The largest seller was Janus Henderson Group, exiting entirely with an estimated $866M sold.

  • 273 institutional investors held Ascendis Pharma A/S (ASND) as of Q1 2026, down from 302 in Q4 2025.
  • Funds reported $14.3B of Ascendis Pharma A/S stock for Q1 2026, up 3.9% quarter-over-quarter.
  • 34 funds opened new Ascendis Pharma A/S positions in Q1 2026 and 58 closed out, a net change of -24 holders.
  • The largest Ascendis Pharma A/S buyer in Q1 2026 was T. Rowe Price Investment Management, an estimated $1.01B added.
  • The largest Ascendis Pharma A/S seller in Q1 2026 was Janus Henderson Group, an estimated $866M sold.

Based on aggregated 13F filings for Q1 2026.