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Arrowhead Research
ARWR

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$71.6M -$6.78M -517,100 -9%
O
2
OrbiMed
New York
$70.9M +$13.7M +1,047,800 +27%
State Street
3
State Street
Massachusetts
$26.8M +$14.3M +1,090,595 +139%
QF
4
QVT Financial
New York
$25.3M -$2.69M -204,800 -10%
Franklin Resources
5
Franklin Resources
California
$23.3M -$802K -61,200 -4%
Vanguard Group
6
Vanguard Group
Pennsylvania
$21.3M +$3.51M +267,950 +22%
BIT
7
BlackRock Institutional Trust
California
$20.7M +$10.5M +803,788 +125%
BBA
8
Baker Bros. Advisors
New York
$20.5M +$9.16M +698,740 +95%
BFA
9
BlackRock Fund Advisors
California
$18.4M +$15.2M +1,162,395 +942%
Millennium Management
10
Millennium Management
New York
$17.9M -$12.8M -976,672 -44%
AllianceBernstein
11
AllianceBernstein
Tennessee
$16.8M +$4.63M +353,214 +43%
VAM
12
Visium Asset Management
New York
$15.9M -$1.37M -104,697 -9%
AWMDMG
13
Austin W. Marxe & David M. Greenhouse
New York
$14.3M -$3.76M -286,873 -22%
JHIU
14
Janus Henderson Investors US
Colorado
$13.2M +$2M +152,588 +20%
JP Morgan Chase
15
JP Morgan Chase
New York
$13M +$3.06M +233,300 +35%
CAM
16
Cormorant Asset Management
Massachusetts
$12.9M -$1.31M -100,000 -10%
Citadel Advisors
17
Citadel Advisors
Florida
$12.6M +$11.2M +853,798 +2,962%
BCPEM
18
Bain Capital Public Equity Management
Massachusetts
$11.9M +$1.47M +112,210 +16%
Jennison Associates
19
Jennison Associates
New York
$10.7M -$398K -30,380 -4%
Ameriprise
20
Ameriprise
Minnesota
$10.6M +$562K +42,889 +6%
BNP Paribas Asset Management
21
BNP Paribas Asset Management
France
$9.53M +$4.52M +344,901 +107%
RCM
22
RA Capital Management
Massachusetts
$8.65M -$30.6M -2,337,570 -79%
Wellington Management Group
23
Wellington Management Group
Massachusetts
$6.88M +$6.31M +480,990 New
PA
24
Perceptive Advisors
New York
$6.04M +$1.38M +105,106 +33%
Lord, Abbett & Co
25
Lord, Abbett & Co
New Jersey
$5.84M +$2.63M +200,512 +97%
1
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