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Arrowhead Research
ARWR

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$90.7M +$97M +5,520,950 New
O
2
OrbiMed
New York
$64.2M +$31.3M +1,781,100 +84%
RCM
3
RA Capital Management
Massachusetts
$48.3M +$15.7M +892,696 +44%
SCA
4
SAC Capital Advisors
Connecticut
$45M +$21.8M +1,240,000 +83%
Millennium Management
5
Millennium Management
New York
$36.5M +$23.9M +1,362,316 +158%
QF
6
QVT Financial
New York
$32.4M -$404K -23,000 -1%
Franklin Resources
7
Franklin Resources
California
$27.8M +$6.66M +379,057 +29%
AWMDMG
8
Austin W. Marxe & David M. Greenhouse
New York
$21.1M -$32.2M -1,831,666 -59%
Vanguard Group
9
Vanguard Group
Pennsylvania
$20M +$11M +625,904 +105%
VAM
10
Visium Asset Management
New York
$20M +$12M +681,151 +127%
CAM
11
Cormorant Asset Management
Massachusetts
$16.4M +$79K +4,500 +0.5%
AllianceBernstein
12
AllianceBernstein
Tennessee
$13.4M +$14.4M +818,302 +223,580%
State Street
13
State Street
Massachusetts
$12.9M +$13.8M +785,110 New
Jennison Associates
14
Jennison Associates
New York
$12.8M +$13.6M +776,746 New
JHIU
15
Janus Henderson Investors US
Colorado
$12.7M +$13.6M +772,020 New
BBA
16
Baker Bros. Advisors
New York
$12M -$41.4M -2,357,938 -76%
BCPEM
17
Bain Capital Public Equity Management
Massachusetts
$11.8M +$12.6M +717,500 New
Ameriprise
18
Ameriprise
Minnesota
$11.5M +$12.3M +701,247 New
JP Morgan Chase
19
JP Morgan Chase
New York
$11.1M +$273K +15,531 +2%
Artisan Partners
20
Artisan Partners
Wisconsin
$10.8M +$11.6M +657,723 New
BIT
21
BlackRock Institutional Trust
California
$10.6M +$3.25M +185,217 +40%
HM
22
HealthCor Management
New York
$7.39M +$7.9M +450,000 New
SCM
23
Sigma Capital Management
Connecticut
$6.57M -$1.76M -100,000 -20%
BNP Paribas Asset Management
24
BNP Paribas Asset Management
France
$5.27M +$5.64M +320,941 New
PA
25
Perceptive Advisors
New York
$5.21M +$5.57M +317,300 New
1
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