Applied Therapeutics
APLT
APLT was delisted on the 2nd of February, 2026.
119 hedge funds and large institutions have $98.5M invested in Applied Therapeutics in 2024 Q4 according to their latest regulatory filings, with 40 funds opening new positions, 43 increasing their positions, 26 reducing their positions, and 46 closing their positions.
65% more repeat investments, than reductions
Existing positions increased: 43 | Existing positions reduced: 26
47% more call options, than puts
Call options by funds: $1.42M | Put options by funds: $969K
0.73% more ownership
Funds ownership: 98.16% → 98.89% (+0.73%)
6% less funds holding
Funds holding: 126 → 119 (-7)
13% less first-time investments, than exits
New positions opened: 40 | Existing positions closed: 46
50% less funds holding in top 10
Funds holding in top 10: 4 → 2 (-2)
90% less capital invested
Capital invested by funds: $961M → $98.5M (-$862M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VPC
Vestal Point Capital
New York
|
+$64.9M |
| 2 |
SSA
Schonfeld Strategic Advisors
New York
|
+$52.8M |
| 3 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
+$32.7M |
| 4 |
PBM
Propel Bio Management
Los Angeles,
California
|
+$19.1M |
| 5 |
BlackRock
New York
|
+$14.8M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Janus Henderson Group
London,
United Kingdom
|
-$65.9M |
| 2 |
PA
Perceptive Advisors
New York
|
-$44.8M |
| 3 |
Franklin Resources
San Mateo,
California
|
-$30.1M |
| 4 |
Adage Capital Partners
Boston,
Massachusetts
|
-$13.5M |
| 5 |
SC
Stempoint Capital
New York
|
-$13.2M |
APLT Hedge Fund Activity: Q4 2024 in Review
119 of the 7,593 institutional investors tracked by Wall St. Rank reported a position in Applied Therapeutics (APLT) for Q4 2024, worth a combined $98.5M — down 90% from $961M a quarter earlier.
Sellers outnumbered buyers: 46 funds closed out of APLT and 40 opened new positions — a net loss of 6 holders — while 26 trimmed existing stakes and 43 added.
The largest buyer was Vestal Point Capital, adding an estimated $64.9M. The largest seller was Janus Henderson Group, cutting an estimated $65.9M.
- 119 institutional investors held Applied Therapeutics (APLT) as of Q4 2024, down from 126 in Q3 2024.
- Funds reported $98.5M of Applied Therapeutics stock for Q4 2024, down 90% quarter-over-quarter.
- 40 funds opened new Applied Therapeutics positions in Q4 2024 and 46 closed out, a net change of -6 holders.
- The largest Applied Therapeutics buyer in Q4 2024 was Vestal Point Capital, an estimated $64.9M added.
- The largest Applied Therapeutics seller in Q4 2024 was Janus Henderson Group, an estimated $65.9M sold.
Based on aggregated 13F filings for Q4 2024.