Applied Therapeutics
APLT
APLT was delisted on the 2nd of February, 2026.
67 hedge funds and large institutions have $278M invested in Applied Therapeutics in 2021 Q1 according to their latest regulatory filings, with 5 funds opening new positions, 36 increasing their positions, 14 reducing their positions, and 5 closing their positions.
31,300% more call options, than puts
Call options by funds: $314K | Put options by funds: $1K
157% more repeat investments, than reductions
Existing positions increased: 36 | Existing positions reduced: 14
3.29% more ownership
Funds ownership: 53.82% → 57.11% (+3.3%)
5% more capital invested
Capital invested by funds: $266M → $278M (+$12.2M)
0% more funds holding
Funds holding: 67 → 67 (0)
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
0% more first-time investments, than exits
New positions opened: 5 | Existing positions closed: 5
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
O
OrbiMed
New York
|
+$10.5M |
| 2 |
Franklin Resources
San Mateo,
California
|
+$8.28M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$6.67M |
| 4 |
Alkeon Capital Management
New York
|
+$6.51M |
| 5 |
KCM
Knoll Capital Management
Miami,
Florida
|
+$3.75M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Millennium Management
New York
|
-$1.38M |
| 2 |
IC
Ikarian Capital
Dallas,
Texas
|
-$726K |
| 3 |
Simplex Trading
Chicago,
Illinois
|
-$592K |
| 4 |
VOYA Investment Management
Atlanta,
Georgia
|
-$434K |
| 5 |
CS
Credit Suisse
Zurich,
Switzerland
|
-$363K |
APLT Hedge Fund Activity: Q1 2021 in Review
67 of the 5,696 institutional investors tracked by Wall St. Rank reported a position in Applied Therapeutics (APLT) for Q1 2021, worth a combined $278M — up 4.6% from $266M a quarter earlier.
Fund positioning in APLT was balanced in Q1 2021: 5 funds opened new positions, 5 closed out, 36 added to existing stakes and 14 trimmed.
The largest buyer was OrbiMed, adding an estimated $10.5M. The largest seller was Millennium Management, cutting an estimated $1.38M.
- 67 institutional investors held Applied Therapeutics (APLT) as of Q1 2021, unchanged from Q4 2020.
- Funds reported $278M of Applied Therapeutics stock for Q1 2021, up 4.6% quarter-over-quarter.
- 5 funds opened new Applied Therapeutics positions in Q1 2021 and 5 closed out, a net change of 0 holders.
- The largest Applied Therapeutics buyer in Q1 2021 was OrbiMed, an estimated $10.5M added.
- The largest Applied Therapeutics seller in Q1 2021 was Millennium Management, an estimated $1.38M sold.
Based on aggregated 13F filings for Q1 2021.