Applied Therapeutics
APLT
APLT was delisted on the 2nd of February, 2026.
75 hedge funds and large institutions have $27.4M invested in Applied Therapeutics in 2025 Q2 according to their latest regulatory filings, with 14 funds opening new positions, 16 increasing their positions, 30 reducing their positions, and 29 closing their positions.
72% more call options, than puts
Call options by funds: $131K | Put options by funds: $76K
0% more funds holding in top 10
Funds holding in top 10: 1 → 1 (0)
17% less funds holding
Funds holding: 90 → 75 (-15)
28.93% less ownership
Funds ownership: 91.14% → 62.2% (-29%)
47% less repeat investments, than reductions
Existing positions increased: 16 | Existing positions reduced: 30
47% less capital invested
Capital invested by funds: $51.8M → $27.4M (-$24.5M)
52% less first-time investments, than exits
New positions opened: 14 | Existing positions closed: 29
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
+$3.21M |
| 2 |
Pathstone Holdings
Englewood,
New Jersey
|
+$1.02M |
| 3 |
Millennium Management
New York
|
+$710K |
| 4 |
Citadel Advisors
Miami,
Florida
|
+$183K |
| 5 |
Goldman Sachs
New York
|
+$160K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
VA
VR Adviser
New York
|
-$2.72M |
| 2 |
SSA
Schonfeld Strategic Advisors
New York
|
-$1.73M |
| 3 |
BlackRock
New York
|
-$1.68M |
| 4 |
Alyeska Investment Group
Chicago,
Illinois
|
-$1.52M |
| 5 |
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
-$1.49M |
APLT Hedge Fund Activity: Q2 2025 in Review
75 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Applied Therapeutics (APLT) for Q2 2025, worth a combined $27.4M — down 47% from $51.8M a quarter earlier.
Sellers outnumbered buyers: 29 funds closed out of APLT and 14 opened new positions — a net loss of 15 holders — while 30 trimmed existing stakes and 16 added.
The largest buyer was T. Rowe Price Investment Management, adding an estimated $3.21M. The largest seller was VR Adviser, exiting entirely with an estimated $2.72M sold.
- 75 institutional investors held Applied Therapeutics (APLT) as of Q2 2025, down from 90 in Q1 2025.
- Funds reported $27.4M of Applied Therapeutics stock for Q2 2025, down 47% quarter-over-quarter.
- 14 funds opened new Applied Therapeutics positions in Q2 2025 and 29 closed out, a net change of -15 holders.
- The largest Applied Therapeutics buyer in Q2 2025 was T. Rowe Price Investment Management, an estimated $3.21M added.
- The largest Applied Therapeutics seller in Q2 2025 was VR Adviser, an estimated $2.72M sold.
Based on aggregated 13F filings for Q2 2025.