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APLT

Applied Therapeutics

Delisted

APLT was delisted on the 2nd of February, 2026.

38 hedge funds and large institutions have $15.1M invested in Applied Therapeutics in 2022 Q4 according to their latest regulatory filings, with 5 funds opening new positions, 6 increasing their positions, 18 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

6.27% less ownership

Funds ownership: 47.22%40.95% (-6.3%)

12% less capital invested

Capital invested by funds: $17.1M → $15.1M (-$2.07M)

14% less funds holding

Funds holding: 4438 (-6)

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

67% less repeat investments, than reductions

Existing positions increased: 6 | Existing positions reduced: 18

Holders
38
Holders Change
-6
Holders Change %
-13.64%
% of All Funds
0.61%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
5
Increased
6
Reduced
18
Closed
11
Calls
$85K
Puts
Net Calls
+$85K
Net Calls Change
-$4.06M
Name Holding Trade Value Shares
Change
Change in
Stake
Franklin Resources
1
Franklin Resources
California
$3.63M
O
2
OrbiMed
New York
$2.32M -$948K -1,199,079 -28%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$2.26M -$183K -231,600 -7%
KCM
4
Knoll Capital Management
Florida
$1.86M +$1.08M +1,367,877 +126%
Alyeska Investment Group
5
Alyeska Investment Group
Illinois
$964K -$1.54M -1,945,161 -61%
Vanguard Group
6
Vanguard Group
Pennsylvania
$605K +$272K +343,299 +76%
Point72 Asset Management
7
Point72 Asset Management
Connecticut
$547K -$791K -1,000,000 -58%
RSCM
8
Rock Springs Capital Management
Maryland
$453K -$83K -105,000 -15%
Bank of Montreal
9
Bank of Montreal
Ontario, Canada
$355K +$256K +323,100 New
AG
10
Artal Group
Luxembourg
$304K
Geode Capital Management
11
Geode Capital Management
Massachusetts
$274K +$22.9K +29,012 +9%
LCM
12
Laurion Capital Management
New York
$263K
Renaissance Technologies
13
Renaissance Technologies
New York
$242K -$12.9K -16,311 -5%
BlackRock
14
BlackRock
New York
$223K -$185K -234,265 -44%
Two Sigma Advisers
15
Two Sigma Advisers
New York
$190K +$554 +700 +0.3%
Two Sigma Investments
16
Two Sigma Investments
New York
$135K -$3.03K -3,828 -2%
PVI
17
Pura Vida Investments
New York
$77.3K +$80.4K +101,654 New
State Street
18
State Street
Massachusetts
$71.8K
Acadian Asset Management
19
Acadian Asset Management
Massachusetts
$65K
Millennium Management
20
Millennium Management
New York
$47K -$29.7K -37,538 -38%
BCM
21
Bridgeway Capital Management
Texas
$44.7K -$39.5K -50,000 -46%
Northern Trust
22
Northern Trust
Illinois
$38.7K
E
23
Ergoteles
New York
$27.8K -$12K -15,161 -29%
Susquehanna International Group
24
Susquehanna International Group
Pennsylvania
$16.7K -$640 -809 -4%
Jane Street
25
Jane Street
New York
$13.5K +$14K +17,707 New

APLT Hedge Fund Activity: Q4 2022 in Review

38 of the 6,222 institutional investors tracked by Wall St. Rank reported a position in Applied Therapeutics (APLT) for Q4 2022, worth a combined $15.1M — down 12% from $17.1M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of APLT and 5 opened new positions — a net loss of 6 holders — while 18 trimmed existing stakes and 6 added.

The largest buyer was Knoll Capital Management, adding an estimated $1.08M. The largest seller was Alyeska Investment Group, cutting an estimated $1.54M.

  • 38 institutional investors held Applied Therapeutics (APLT) as of Q4 2022, down from 44 in Q3 2022.
  • Funds reported $15.1M of Applied Therapeutics stock for Q4 2022, down 12% quarter-over-quarter.
  • 5 funds opened new Applied Therapeutics positions in Q4 2022 and 11 closed out, a net change of -6 holders.
  • The largest Applied Therapeutics buyer in Q4 2022 was Knoll Capital Management, an estimated $1.08M added.
  • The largest Applied Therapeutics seller in Q4 2022 was Alyeska Investment Group, an estimated $1.54M sold.

Based on aggregated 13F filings for Q4 2022.