|
1
|
Wellington Management Group
Boston,
Massachusetts
|
$984M
|
+$64.8M
|
+1,278,246
|
+8%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$669M
|
+$13.9M
|
+273,209
|
+3%
|
|
|
3
|
Avoro Capital Advisors
New York
|
$665M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$572M
|
+$4.35M
|
+85,701
|
+0.9%
|
|
|
5
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$377M
|
-$11M
|
-215,887
|
-3%
|
|
|
6
|
|
$322M
|
+$5.5M
|
+108,507
|
+2%
|
|
|
7
|
Jennison Associates
New York
|
$196M
|
-$13.5M
|
-266,287
|
-8%
|
|
|
8
|
|
$185M
|
+$75.5M
|
+1,488,145
|
+92%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$175M
|
-$16.4M
|
-322,692
|
-10%
|
|
|
10
|
Octagon Capital Advisors
New York
|
$168M
|
-$16.4M
|
-323,020
|
-10%
|
|
|
11
|
|
$154M
|
+$18.1M
|
+356,386
|
+16%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$147M
|
+$34.3M
|
+677,098
|
+38%
|
|
|
13
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$128M
|
+$56.9M
|
+1,121,497
|
+110%
|
|
|
14
|
Fidelity Investments
Boston,
Massachusetts
|
$125M
|
-$8.49M
|
-167,302
|
-7%
|
|
|
15
|
Boxer Capital
San Diego,
California
|
$103M
|
–
|
–
|
–
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$97.6M
|
+$3.85M
|
+75,816
|
+5%
|
|
|
17
|
|
$85.1M
|
-$12.3M
|
-243,226
|
-15%
|
|
|
18
|
Pictet Asset Management
Carouge,
Switzerland
|
$80.5M
|
+$31M
|
+610,413
|
+83%
|
|
|
19
|
Polar Capital Holdings
London,
United Kingdom
|
$63.1M
|
-$22.1K
|
-435
|
-0%
|
|
|
20
|
Logos Global Management
San Francisco,
California
|
$56.9M
|
+$10.1M
|
+200,000
|
+27%
|
|
|
21
|
|
$56.6M
|
-$5.38M
|
-105,980
|
-10%
|
|
|
22
|
|
$55.2M
|
-$17.2M
|
-338,300
|
-27%
|
|
|
23
|
Fiera Capital (Canada)
Montreal,
Quebec, Canada
|
$55M
|
-$30.4K
|
-600
|
-0.1%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$54.1M
|
+$1.27M
|
+25,052
|
+3%
|
|
|
25
|
Frazier Life Sciences Management
Palo Alto,
California
|
$53M
|
+$13.8M
|
+271,122
|
+44%
|
|
