|
1
|
Avoro Capital Advisors
New York
|
$549M
|
+$26.5M
|
+500,000
|
+5%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$476M
|
+$9.62M
|
+181,412
|
+2%
|
|
|
3
|
Wellington Management Group
Boston,
Massachusetts
|
$453M
|
-$63.6M
|
-1,199,755
|
-12%
|
|
|
4
|
|
$398M
|
+$32.8M
|
+617,864
|
+9%
|
|
|
5
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$302M
|
+$17.3M
|
+326,537
|
+6%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$268M
|
–
|
–
|
–
|
|
|
7
|
Janus Henderson Group
London,
|
$206M
|
+$211M
|
+3,973,609
|
+28,110%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$180M
|
+$27.3M
|
+514,641
|
+17%
|
|
|
9
|
Octagon Capital Advisors
New York
|
$163M
|
+$34.8M
|
+656,941
|
+26%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$142M
|
-$31.9M
|
-601,421
|
-18%
|
|
|
11
|
Jennison Associates
New York
|
$130M
|
-$1.03M
|
-19,395
|
-0.8%
|
|
|
12
|
|
$95.5M
|
+$48.1M
|
+907,262
|
+97%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$90.5M
|
+$3.12M
|
+58,799
|
+3%
|
|
|
14
|
Cormorant Asset Management
Boston,
Massachusetts
|
$81.5M
|
+$5.24M
|
+98,872
|
+7%
|
|
|
15
|
Boxer Capital
San Diego,
California
|
$81.5M
|
+$14.4M
|
+272,300
|
+21%
|
|
|
16
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$75.6M
|
+$2.13M
|
+40,107
|
+3%
|
|
|
17
|
Fidelity Investments
Boston,
Massachusetts
|
$75.5M
|
-$53
|
-1
|
-0%
|
|
|
18
|
Logos Global Management
San Francisco,
California
|
$69.8M
|
+$2.65M
|
+50,000
|
+4%
|
|
|
19
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$58.6M
|
+$9.87M
|
+186,097
|
+20%
|
|
|
20
|
Bellevue Group
Kuesnacht,
Switzerland
|
$57.1M
|
+$5.13M
|
+96,773
|
+10%
|
|
|
21
|
|
$54.9M
|
+$5.52M
|
+104,025
|
+11%
|
|
|
22
|
|
$54.2M
|
+$3.95M
|
+74,480
|
+8%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$50.8M
|
+$1.81M
|
+34,168
|
+4%
|
|
|
24
|
|
$46.5M
|
-$5.3M
|
-100,000
|
-10%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$44.3M
|
+$421K
|
+7,933
|
+0.9%
|
|
