|
1
|
Avoro Capital Advisors
New York
|
$692M
|
+$18.9M
|
+320,000
|
+3%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$680M
|
-$93.8M
|
-1,585,327
|
-14%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$617M
|
+$18M
|
+304,334
|
+3%
|
|
|
4
|
|
$484M
|
+$17M
|
+287,786
|
+4%
|
|
|
5
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$377M
|
+$326M
|
+5,516,123
|
New
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$354M
|
–
|
–
|
–
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$229M
|
-$315M
|
-5,328,850
|
-61%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$202M
|
-$31.9M
|
-539,652
|
-15%
|
|
|
9
|
Jennison Associates
New York
|
$173M
|
+$14M
|
+236,365
|
+10%
|
|
|
10
|
Octagon Capital Advisors
New York
|
$171M
|
-$4.73M
|
-80,000
|
-3%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$116M
|
+$4.8M
|
+81,040
|
+5%
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$101M
|
+$31.2M
|
+528,000
|
+56%
|
|
|
13
|
Fidelity Investments
Boston,
Massachusetts
|
$99.7M
|
+$4.25M
|
+71,737
|
+5%
|
|
|
14
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$97.2M
|
+$2.25M
|
+38,028
|
+3%
|
|
|
15
|
Boxer Capital
San Diego,
California
|
$89M
|
–
|
–
|
–
|
|
|
16
|
Logos Global Management
San Francisco,
California
|
$88.8M
|
-$11.8M
|
-200,000
|
-13%
|
|
|
17
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$83.7M
|
+$20.2M
|
+341,898
|
+39%
|
|
|
18
|
Bellevue Group
Kuesnacht,
Switzerland
|
$68.8M
|
-$11.8M
|
-198,978
|
-16%
|
|
|
19
|
|
$68.3M
|
+$59.2M
|
+1,000,000
|
New
|
|
|
20
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$67.5M
|
+$586K
|
+9,909
|
+1%
|
|
|
21
|
|
$66.5M
|
+$1.6M
|
+27,094
|
+3%
|
|
|
22
|
|
$65.4M
|
+$8.72M
|
+147,279
|
+18%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$64.8M
|
+$16M
|
+270,358
|
+40%
|
|
|
24
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$64.6M
|
+$56M
|
+946,526
|
New
|
|
|
25
|
|
$64.2M
|
-$7.92M
|
-133,918
|
-12%
|
|
