Vanguard Group’s Apellis Pharmaceuticals APLS Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2025
Q4
$268M Buy
10,674,865
+687,471
+7% +$16.1M ﹤0.01% 1390
2025
Q3
$226M Sell
9,987,394
-167,357
-2% -$3.9M ﹤0.01% 1484
2025
Q2
$176M Buy
10,154,751
+24,395
+0.2% +$452K ﹤0.01% 1568
2025
Q1
$222M Buy
10,130,356
+84,331
+0.8% +$2.33M ﹤0.01% 1438
2024
Q4
$321M Buy
10,046,025
+230,450
+2% +$6.93M 0.01% 1302
2024
Q3
$283M Buy
9,815,575
+6,023
+0.1% +$223K 0.01% 1353
2024
Q2
$376M Buy
9,809,552
+303,686
+3% +$13.8M 0.01% 1131
2024
Q1
$559M Sell
9,505,866
-49,812
-0.5% -$3.18M 0.01% 944
2023
Q4
$572M Buy
9,555,678
+85,701
+0.9% +$4.35M 0.01% 891
2023
Q3
$360M Buy
9,469,977
+68,687
+0.7% +$3.02M 0.01% 1092
2023
Q2
$856M Sell
9,401,290
-127,654
-1% -$11M 0.02% 662
2023
Q1
$629M Buy
9,528,944
+316,453
+3% +$18.3M 0.02% 775
2022
Q4
$476M Buy
9,212,491
+181,412
+2% +$9.62M 0.01% 899
2022
Q3
$617M Buy
9,031,079
+304,334
+3% +$18M 0.02% 718
2022
Q2
$395M Buy
8,726,745
+157,575
+2% +$7.18M 0.01% 1006
2022
Q1
$435M Buy
8,569,170
+652,071
+8% +$28.8M 0.01% 1063
2021
Q4
$374M Buy
7,917,099
+1,164,814
+17% +$45.9M 0.01% 1183
2021
Q3
$223M Buy
6,752,285
+407,829
+6% +$22.9M 0.01% 1537
2021
Q2
$401M Buy
6,344,456
+239,939
+4% +$12.4M 0.01% 1131
2021
Q1
$262M Buy
6,104,517
+562,692
+10% +$26.6M 0.01% 1422
2020
Q4
$317M Buy
5,541,825
+1,223,468
+28% +$51.8M 0.01% 1156
2020
Q3
$130M Sell
4,318,357
-69,824
-2% -$2.09M ﹤0.01% 1548
2020
Q2
$143M Buy
4,388,181
+1,354,710
+45% +$43.5M 0.01% 1484
2020
Q1
$81.3M Buy
3,033,471
+619,157
+26% +$22M ﹤0.01% 1642
2019
Q4
$73.9M Buy
2,414,314
+257,228
+12% +$7.12M ﹤0.01% 1912
2019
Q3
$52M Buy
2,157,086
+106,248
+5% +$2.92M ﹤0.01% 2044
2019
Q2
$52M Buy
2,050,838
+47,555
+2% +$968K ﹤0.01% 2079
2019
Q1
$39.1M Buy
2,003,283
+563,245
+39% +$8.86M ﹤0.01% 2212
2018
Q4
$19M Buy
1,440,038
+25,138
+2% +$386K ﹤0.01% 2465
2018
Q3
$25.2M Buy
1,414,900
+72,610
+5% +$1.34M ﹤0.01% 2476
2018
Q2
$29.5M Buy
1,342,290
+959,637
+251% +$22M ﹤0.01% 2388
2018
Q1
$8.46M Buy
382,653
+108,579
+40% +$2.13M ﹤0.01% 2900
2017
Q4
$5.95M Buy
+274,074
New +$4.03M ﹤0.01% 3059

Other funds holding APLS

Vanguard Group's APLS Position: Q4 2025 in Review

Vanguard Group increased its Apellis Pharmaceuticals (APLS) stake by 6.9% in Q4 2025, buying an estimated $16.1M and bringing the position to 10,674,865 shares worth $268M. The position accounts for ﹤0.01% of the portfolio, ranked #1390.

Vanguard Group first reported a position in APLS in Q4 2017 and has held it in 33 quarters since. The position peaked at $856M in Q2 2023. 279 funds tracked by Wall St. Rank hold APLS as of Q4 2025.

  • Vanguard Group held 10,674,865 shares of Apellis Pharmaceuticals worth $268M as of Q4 2025.
  • Vanguard Group bought 687,471 Apellis Pharmaceuticals shares in Q4 2025, an estimated $16.1M.
  • Apellis Pharmaceuticals made up ﹤0.01% of Vanguard Group's portfolio in Q4 2025, its #1390 holding.
  • Vanguard Group first reported a position in Apellis Pharmaceuticals in Q4 2017 and has held it in 33 quarters since.
  • Vanguard Group's Apellis Pharmaceuticals position peaked at $856M in Q2 2023.
  • 279 funds tracked by Wall St. Rank held Apellis Pharmaceuticals as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.