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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

212 hedge funds and large institutions have $4.55B invested in Apellis Pharmaceuticals in 2022 Q1 according to their latest regulatory filings, with 53 funds opening new positions, 73 increasing their positions, 63 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

121% more first-time investments, than exits

New positions opened: 53 | Existing positions closed: 24

38% more funds holding in top 10

Funds holding in top 10: 811 (+3)

19% more capital invested

Capital invested by funds: $3.83B → $4.55B (+$721M)

16% more repeat investments, than reductions

Existing positions increased: 73 | Existing positions reduced: 63

14% more funds holding

Funds holding: 186212 (+26)

2.12% more ownership

Funds ownership: 84.36%86.48% (+2.1%)

1% less call options, than puts

Call options by funds: $82.1M | Put options by funds: $82.8M

Holders
212
Holders Change
+26
Holders Change %
+13.98%
% of All Funds
3.34%
Holding in Top 10
11
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+37.5%
% of All Funds
0.17%
New
53
Increased
73
Reduced
63
Closed
24
Calls
$82.1M
Puts
$82.8M
Net Calls
-$722K
Net Calls Change
-$19.3M
Name Holding Trade Value Shares
Change
Change in
Stake
Wellington Management Group
1
Wellington Management Group
Massachusetts
$721M +$82.5M +1,868,641 +15%
ACA
2
Avoro Capital Advisors
New York
$480M +$39.5M +894,445 +10%
Vanguard Group
3
Vanguard Group
Pennsylvania
$435M +$28.8M +652,071 +8%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$401M +$114M +2,586,348 +49%
BlackRock
5
BlackRock
New York
$301M +$2.57M +58,208 +1%
EC
6
EcoR1 Capital
California
$263M +$50.7M +1,149,549 +28%
State Street
7
State Street
Massachusetts
$148M +$8.26M +187,088 +7%
Jennison Associates
8
Jennison Associates
New York
$137M +$37.2M +842,233 +45%
OCA
9
Octagon Capital Advisors
New York
$119M +$14.1M +319,148 +16%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$75.9M +$6.21M +140,691 +10%
PA
11
Perceptive Advisors
New York
$75.3M +$1.32M +30,000 +2%
Fidelity Investments
12
Fidelity Investments
Massachusetts
$71M -$9.59M -217,267 -13%
Victory Capital Management
13
Victory Capital Management
Texas
$67.2M -$10.6M -241,013 -15%
BC
14
Boxer Capital
California
$66.2M +$57.6M +1,303,700 New
JP Morgan Chase
15
JP Morgan Chase
New York
$64.3M -$14.2M -321,640 -20%
CAM
16
Cormorant Asset Management
Massachusetts
$57.2M +$22.1M +500,000 +80%
BG
17
Bellevue Group
Switzerland
$55.8M +$19.8M +448,121 +69%
Marshall Wace
18
Marshall Wace
United Kingdom
$46.5M +$40.4M +915,163 New
LGM
19
Logos Global Management
California
$45.7M -$4.41M -100,000 -10%
PAMS
20
Pictet Asset Management (Switzerland)
Switzerland
$45.6M +$11.1M +251,597 +39%
Norges Bank
21
Norges Bank
Norway
$41.4M +$7.72M +174,798 +27%
Northern Trust
22
Northern Trust
Illinois
$38.9M +$942K +21,335 +3%
Charles Schwab
23
Charles Schwab
California
$33.3M +$2.8M +63,394 +11%
DCM
24
Driehaus Capital Management
Illinois
$31.9M +$16.1M +365,748 +139%
FT
25
Fiduciary Trust
Massachusetts
$28.7M -$662 -15 -0%

APLS Hedge Fund Activity: Q1 2022 in Review

212 of the 6,341 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q1 2022, worth a combined $4.55B — up 19% from $3.83B a quarter earlier.

Buyers outnumbered sellers: 53 funds opened new APLS positions and 24 closed out — a net gain of 29 holders — while 73 added to existing stakes and 63 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $114M. The largest seller was RTW Investments, cutting an estimated $85.6M.

  • 212 institutional investors held Apellis Pharmaceuticals (APLS) as of Q1 2022, up from 186 in Q4 2021.
  • Funds reported $4.55B of Apellis Pharmaceuticals stock for Q1 2022, up 19% quarter-over-quarter.
  • 53 funds opened new Apellis Pharmaceuticals positions in Q1 2022 and 24 closed out, a net change of +29 holders.
  • The largest Apellis Pharmaceuticals buyer in Q1 2022 was T. Rowe Price Associates, an estimated $114M added.
  • The largest Apellis Pharmaceuticals seller in Q1 2022 was RTW Investments, an estimated $85.6M sold.

Based on aggregated 13F filings for Q1 2022.