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APLS

Apellis Pharmaceuticals

Delisted

APLS was delisted on the 13th of May, 2026.

323 hedge funds and large institutions have $5.56B invested in Apellis Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 128 funds opening new positions, 89 increasing their positions, 72 reducing their positions, and 79 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 26 (+4)

75% more capital invested

Capital invested by funds: $3.17B → $5.56B (+$2.39B)

62% more first-time investments, than exits

New positions opened: 128 | Existing positions closed: 79

43% more call options, than puts

Call options by funds: $52.1M | Put options by funds: $36.5M

24% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 72

16% more funds holding

Funds holding: 279323 (+44)

9.9% more ownership

Funds ownership: 99.89%109.78% (+9.9%)

Holders
323
Holders Change
+44
Holders Change %
+15.77%
% of All Funds
3.95%
Holding in Top 10
6
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+200%
% of All Funds
0.07%
New
128
Increased
89
Reduced
72
Closed
79
Calls
$52.1M
Puts
$36.5M
Net Calls
+$15.7M
Net Calls Change
-$61.6M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$545M +$157M +7,276,851 +116%
ACA
2
Avoro Capital Advisors
New York
$492M
Morgan Stanley
3
Morgan Stanley
New York
$404M +$18.7M +869,395 +9%
State Street
4
State Street
Massachusetts
$275M +$48.1M +2,231,544 +48%
UBS Group
5
UBS Group
Switzerland
$250M +$43.5M +2,020,459 +48%
Vanguard Portfolio Management
6
Vanguard Portfolio Management
Pennsylvania
$217M +$116M +5,404,559 New
PCM
7
Pentwater Capital Management
Florida
$211M +$113M +5,250,000 New
Vanguard Capital Management
8
Vanguard Capital Management
Pennsylvania
$192M +$103M +4,768,944 New
DTC
9
Deep Track Capital
Connecticut
$182M -$69.3M -3,217,626 -42%
Point72 Asset Management
10
Point72 Asset Management
Connecticut
$168M +$77.3M +3,586,246 +600%
RI
11
RTW Investments
New York
$148M -$85.8M -3,981,719 -52%
HI
12
HBK Investments
Texas
$143M +$76.5M +3,550,000 New
SCM
13
Suvretta Capital Management
New York
$142M -$13.4M -620,955 -15%
Millennium Management
14
Millennium Management
New York
$90.8M +$28.2M +1,310,343 +138%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$83.5M +$1.06M +49,406 +2%
Goldman Sachs
16
Goldman Sachs
New York
$79.7M +$38.6M +1,790,939 +947%
Balyasny Asset Management
17
Balyasny Asset Management
Illinois
$77.1M +$39.9M +1,852,368 +2,844%
Dimensional Fund Advisors
18
Dimensional Fund Advisors
Texas
$53.7M +$25M +1,158,070 +640%
GCL
19
Glazer Capital LLC
New York
$52.1M +$27.9M +1,294,196 New
TAL
20
TIG Advisors LLC
New York
$50.4M +$27M +1,252,986 New
Toronto Dominion Bank
21
Toronto Dominion Bank
Ontario, Canada
$49.7M +$26.6M +1,236,436 New
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
22
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$48.4M +$25.9M +1,202,100 New
Bank of America
23
Bank of America
North Carolina
$47.9M +$5.04M +234,091 +24%
Hudson Bay Capital Management
24
Hudson Bay Capital Management
Connecticut
$47.9M +$228K +10,588 +0.9%
Fidelity International
25
Fidelity International
Bermuda
$45.9M +$24.6M +1,140,000 New

APLS Hedge Fund Activity: Q1 2026 in Review

323 of the 8,169 institutional investors tracked by Wall St. Rank reported a position in Apellis Pharmaceuticals (APLS) for Q1 2026, worth a combined $5.56B — up 75% from $3.17B a quarter earlier.

Buyers outnumbered sellers: 128 funds opened new APLS positions and 79 closed out — a net gain of 49 holders — while 89 added to existing stakes and 72 trimmed.

The largest buyer was BlackRock, adding an estimated $157M. The largest seller was Wellington Management Group, cutting an estimated $269M.

  • 323 institutional investors held Apellis Pharmaceuticals (APLS) as of Q1 2026, up from 279 in Q4 2025.
  • Funds reported $5.56B of Apellis Pharmaceuticals stock for Q1 2026, up 75% quarter-over-quarter.
  • 128 funds opened new Apellis Pharmaceuticals positions in Q1 2026 and 79 closed out, a net change of +49 holders.
  • The largest Apellis Pharmaceuticals buyer in Q1 2026 was BlackRock, an estimated $157M added.
  • The largest Apellis Pharmaceuticals seller in Q1 2026 was Wellington Management Group, an estimated $269M sold.

Based on aggregated 13F filings for Q1 2026.