Annexon
ANNX
216 hedge funds and large institutions have $1.02B invested in Annexon in 2026 Q2 according to their latest regulatory filings, with 31 funds opening new positions, 79 increasing their positions, 80 reducing their positions, and 28 closing their positions.
228% more call options, than puts
Call options by funds: $8.23M | Put options by funds: $2.51M
111% more capital inflows, than outflows
Capital inflows: $237M | Capital outflows: $113M
13.68% more ownership
Funds ownership: 95.18% → 108.86% (+14%)
11% more first-time investments, than exits
New positions opened: 31 | Existing positions closed: 28
0% less funds holding
Funds holding: 217 → 216 (-1)
1% less repeat investments, than reductions
Existing positions increased: 79 | Existing positions reduced: 80
20% less funds holding in top 10
Funds holding in top 10: 5 → 4 (-1)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Fidelity Investments
Boston,
Massachusetts
|
+$49.1M |
| 2 |
WP
Woodline Partners
San Francisco,
California
|
+$25.4M |
| 3 |
Goldman Sachs
New York
|
+$20.3M |
| 4 |
MB
MPM BioImpact
Boston,
Massachusetts
|
+$19.6M |
| 5 |
State Street
Boston,
Massachusetts
|
+$16.1M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Bank of America
Charlotte,
North Carolina
|
-$20.2M |
| 2 |
RG
Redmile Group
San Francisco,
California
|
-$14.8M |
| 3 |
Nuveen
Charlotte,
North Carolina
|
-$8.19M |
| 4 |
BG
Bellevue Group
Kuesnacht,
Switzerland
|
-$5.84M |
| 5 |
Balyasny Asset Management
Chicago,
Illinois
|
-$5.84M |
ANNX Hedge Fund Activity: Q2 2026 in Review
216 of the 8,352 institutional investors tracked by Wall St. Rank reported a position in Annexon (ANNX) for Q2 2026, worth a combined $1.02B — up 18% from $864M a quarter earlier.
Buyers outnumbered sellers: 31 funds opened new ANNX positions and 28 closed out — a net gain of 3 holders — while 79 added to existing stakes and 80 trimmed.
The largest buyer was Fidelity Investments, adding an estimated $49.1M. The largest seller was Bank of America, cutting an estimated $20.2M.
- 216 institutional investors held Annexon (ANNX) as of Q2 2026, down from 217 in Q1 2026.
- Funds reported $1.02B of Annexon stock for Q2 2026, up 18% quarter-over-quarter.
- 31 funds opened new Annexon positions in Q2 2026 and 28 closed out, a net change of +3 holders.
- The largest Annexon buyer in Q2 2026 was Fidelity Investments, an estimated $49.1M added.
- The largest Annexon seller in Q2 2026 was Bank of America, an estimated $20.2M sold.
Based on aggregated 13F filings for Q2 2026.