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AnaptysBio
ANAB

207 hedge funds and large institutions have $1.55B invested in AnaptysBio in 2026 Q1 according to their latest regulatory filings, with 51 funds opening new positions, 58 increasing their positions, 70 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

364% more call options, than puts

Call options by funds: $1.41M | Put options by funds: $305K

155% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 20

50% more funds holding in top 10

Funds holding in top 10: 4 → 6 (+2)

16% more funds holding

Funds holding: 179 → 207 (+28)

9% more capital invested

Capital invested by funds: $1.42B → $1.55B (+$128M)

7.8% less ownership

Funds ownership: 106.02% → 98.22% (-7.8%)

17% less repeat investments, than reductions

Existing positions increased: 58 | Existing positions reduced: 70

Holders
207
Holders Change
+28
Holders Change %
+15.64%
% of All Funds
2.55%
Holding in Top 10
6
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+50%
% of All Funds
0.07%
New
51
Increased
58
Reduced
70
Closed
20
Calls
$1.41M
Puts
$305K
Net Calls
+$1.11M
Net Calls Change
+$4.48M

Top Buyers

1
AAA
Affinity Asset Advisors
New York
+$26.6M
2
Fidelity Investments
Fidelity Investments
Massachusetts
+$24M
3
Bank of America
Bank of America
North Carolina
+$19.9M
4
SAM
Synergy Asset Management
Washington
+$17.1M
5
ACA
Apis Capital Advisors
New York
+$12.8M

Top Sellers

1
Point72 Asset Management
Point72 Asset Management
Connecticut
-$101M
2
Millennium Management
Millennium Management
New York
-$18.2M
3
WP
Woodline Partners
California
-$8.43M
4
Voloridge Investment Management
Voloridge Investment Management
Florida
-$8.08M
5
SCM
Soleus Capital Management
Connecticut
-$6.94M
Name Holding Trade Value Shares
Change 		Change in
Stake
KK
151
KLP Kapitalforvaltning
Norway
$166K – – –
TRCT
152
Tower Research Capital (TRC)
New York
$161K +$117K +2,171 +299%
CIAM
153
Caitong International Asset Management
Hong Kong
$129K +$43K +799 +52%
Osaic Holdings
154
Osaic Holdings
Arizona
$113K -$1.38M -25,691 -93%
ACM
155
Aster Capital Management
United Arab Emirates
$97K +$274K +5,093 +4,074%
US Bancorp
156
US Bancorp
Minnesota
$90.7K -$377 -7 -0.4%
LFG
157
Larson Financial Group
Missouri
$90.2K +$108 +2 +0.1%
AIP
158
Ameritas Investment Partners
Nebraska
$82.9K -$8.23K -153 -9%
Bessemer Group
159
Bessemer Group
New Jersey
$79K -$1.78K -33 -2%
Carson Wealth (CWM LLC)
160
Carson Wealth (CWM LLC)
Nebraska
$56.3K +$215 +4 +0.4%
Mirae Asset Global Investments
161
Mirae Asset Global Investments
South Korea
$53.4K +$5.33K +99 +7%
EWA
162
EverSource Wealth Advisors
Alabama
$50.1K +$1.51K +28 +3%
SAM
163
Smartleaf Asset Management
Massachusetts
$46.5K +$269 +5 +0.6%
SS
164
SBI Securities
Japan
$43.7K -$56.3K -1,046 -57%
Canada Life
165
Canada Life
Manitoba, Canada
$42K – – –
Nisa Investment Advisors
166
Nisa Investment Advisors
Missouri
$36K -$16.9K -314 -33%
GFM
167
GF Fund Management
China
$34.4K +$4.2K +78 +14%
QT
168
Quantbot Technologies
New York
$31K +$30.1K +559 New
VCM
169
Versant Capital Management
Arizona
$25.2K – – –
GI
170
GAMMA Investing
California
$24.5K +$3.12K +58 +15%
SWM
171
Spire Wealth Management
Virginia
$22.2K +$21.5K +400 New
FFA
172
Farther Finance Advisors
California
$21.8K – – –
S
173
SignatureFD
Georgia
$20.3K +$753 +14 +4%
Group One Trading
174
Group One Trading
Illinois
$20.2K +$19.6K +365 New
PWPS
175
Pinnacle Wealth Planning Services
Ohio
$18.5K – – –
5 6
7
8 9

ANAB Hedge Fund Activity: Q1 2026 in Review

207 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in AnaptysBio (ANAB) for Q1 2026, worth a combined $1.55B — up 9% from $1.42B a quarter earlier.

Buyers outnumbered sellers: 51 funds opened new ANAB positions and 20 closed out — a net gain of 31 holders — while 58 added to existing stakes and 70 trimmed.

The largest buyer was Affinity Asset Advisors, adding an estimated $26.6M. The largest seller was Point72 Asset Management, cutting an estimated $101M.

  • 207 institutional investors held AnaptysBio (ANAB) as of Q1 2026, up from 179 in Q4 2025.
  • Funds reported $1.55B of AnaptysBio stock for Q1 2026, up 9% quarter-over-quarter.
  • 51 funds opened new AnaptysBio positions in Q1 2026 and 20 closed out, a net change of +31 holders.
  • The largest AnaptysBio buyer in Q1 2026 was Affinity Asset Advisors, an estimated $26.6M added.
  • The largest AnaptysBio seller in Q1 2026 was Point72 Asset Management, an estimated $101M sold.

Based on aggregated 13F filings for Q1 2026.