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AnaptysBio

179 hedge funds and large institutions have $1.42B invested in AnaptysBio in 2025 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 51 increasing their positions, 64 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more first-time investments, than exits

New positions opened: 37 | Existing positions closed: 24

45% more capital invested

Capital invested by funds: $980M → $1.42B (+$443M)

8% more funds holding

Funds holding: 166179 (+13)

7.11% less ownership

Funds ownership: 113.12%106.02% (-7.1%)

14% less call options, than puts

Call options by funds: $20.8M | Put options by funds: $24.2M

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

20% less repeat investments, than reductions

Existing positions increased: 51 | Existing positions reduced: 64

Holders
179
Holders Change
+13
Holders Change %
+7.83%
% of All Funds
2.18%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
37
Increased
51
Reduced
64
Closed
24
Calls
$20.8M
Puts
$24.2M
Net Calls
-$3.37M
Net Calls Change
+$2.37M
Name Holding Trade Value Shares
Change
Change in
Stake
State of Wisconsin Investment Board
101
State of Wisconsin Investment Board
Wisconsin
$434K +$349K +8,955 New
BC
102
Bridgefront Capital
Texas
$414K +$333K +8,549 New
ET
103
Entropy Technologies
New York
$402K +$324K +8,300 New
BAM
104
Blueshift Asset Management
New Jersey
$381K +$306K +7,852 New
A
105
AlphaQuest
New York
$376K -$50K -1,282 -14%
CUAMC
106
China Universal Asset Management Company
China
$364K -$93.4K -2,395 -24%
Janus Henderson Group
107
Janus Henderson Group
United Kingdom
$362K
GT
108
Glenmede Trust
Pennsylvania
$356K +$286K +7,346 New
IIM
109
INTECH Investment Management
Florida
$336K -$34.4K -883 -11%
SC
110
SummitTX Capital
Texas
$316K +$254K +6,528 New
DWAM
111
Duncan Williams Asset Management
Tennessee
$316K +$254K +6,525 New
QCM
112
Quantinno Capital Management
New York
$312K +$251K +6,434 New
SC
113
Savant Capital
Illinois
$305K +$245K +6,295 New
Envestnet Asset Management
114
Envestnet Asset Management
Illinois
$296K +$238K +6,097 New
VIA
115
Virtus Investment Advisers
Connecticut
$287K +$41.3K +1,059 +22%
VRS
116
Virginia Retirement Systems
Virginia
$284K +$228K +5,850 New
Acadian Asset Management
117
Acadian Asset Management
Massachusetts
$280K +$226K +5,809 New
Manulife (Manufacturers Life Insurance)
118
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$275K -$40.4K -1,037 -15%
AG
119
Ascent Group
Virginia
$274K +$221K +5,662 New
PFSRSONJ
120
Police & Firemen's Retirement System of New Jersey
New Jersey
$273K +$42.2K +1,082 +24%
FWM
121
FMB Wealth Management
California
$271K +$218K +5,592 New
State Board of Administration of Florida Retirement System
122
State Board of Administration of Florida Retirement System
Florida
$268K +$215K +5,526 New
SEI Investments
123
SEI Investments
Pennsylvania
$241K -$388K -9,955 -67%
Public Employees Retirement Association of Colorado
124
Public Employees Retirement Association of Colorado
Colorado
$236K
ProShare Advisors
125
ProShare Advisors
Maryland
$223K +$179K +4,598 New