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AnaptysBio

179 hedge funds and large institutions have $1.42B invested in AnaptysBio in 2025 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 51 increasing their positions, 64 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more first-time investments, than exits

New positions opened: 37 | Existing positions closed: 24

45% more capital invested

Capital invested by funds: $980M → $1.42B (+$443M)

8% more funds holding

Funds holding: 166179 (+13)

7.11% less ownership

Funds ownership: 113.12%106.02% (-7.1%)

14% less call options, than puts

Call options by funds: $20.8M | Put options by funds: $24.2M

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

20% less repeat investments, than reductions

Existing positions increased: 51 | Existing positions reduced: 64

Holders
179
Holders Change
+13
Holders Change %
+7.83%
% of All Funds
2.18%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
37
Increased
51
Reduced
64
Closed
24
Calls
$20.8M
Puts
$24.2M
Net Calls
-$3.37M
Net Calls Change
+$2.37M
Name Holding Trade Value Shares
Change
Change in
Stake
Charles Schwab
26
Charles Schwab
California
$9.63M -$303K -7,781 -4%
Northern Trust
27
Northern Trust
Illinois
$8.82M -$533K -13,679 -7%
BNP Paribas Financial Markets
28
BNP Paribas Financial Markets
France
$7.99M +$2.31M +59,160 +56%
Squarepoint
29
Squarepoint
New York
$7.79M +$3.61M +92,717 +136%
SCM
30
Soleus Capital Management
Connecticut
$6.54M -$19.1M -491,040 -78%
Bank of America
31
Bank of America
North Carolina
$6.34M +$137K +3,526 +3%
GIM
32
Granahan Investment Management
Massachusetts
$6.1M -$854K -21,918 -15%
Invesco
33
Invesco
Georgia
$6.01M +$3.18M +81,625 +193%
Connor, Clark & Lunn Investment Management (CC&L)
34
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$5.94M +$4.77M +122,476 New
EP
35
Eversept Partners
New York
$5.86M +$4.71M +120,927 New
JF
36
Jump Financial
Illinois
$5.83M +$1.49M +38,140 +46%
Victory Capital Management
37
Victory Capital Management
Texas
$5.36M -$3.64M -93,472 -46%
Citadel Advisors
38
Citadel Advisors
Florida
$5.31M +$3.24M +83,003 +313%
Qube Research & Technologies (QRT)
39
Qube Research & Technologies (QRT)
United Kingdom
$5.28M +$4.25M +108,965 New
HWM
40
HighMark Wealth Management
Minnesota
$4.56M -$1.6M -41,000 -30%
NAMI
41
Nomura Asset Management International
Pennsylvania
$4.54M +$3.65M +93,732 New
Jane Street
42
Jane Street
New York
$4.09M -$3.77M -96,665 -53%
ECM
43
ExodusPoint Capital Management
New York
$4.04M +$2.21M +56,813 +214%
Renaissance Technologies
44
Renaissance Technologies
New York
$3.7M -$1.83M -47,000 -38%
Citigroup
45
Citigroup
New York
$3.56M +$114K +2,919 +4%
HF
46
HRT Financial
New York
$3.4M +$1.76M +45,105 +180%
UBS Group
47
UBS Group
Switzerland
$3.4M -$204K -5,230 -7%
Wellington Management Group
48
Wellington Management Group
Massachusetts
$2.97M -$216K -5,544 -8%
Barclays
49
Barclays
United Kingdom
$2.89M -$148K -3,798 -6%
TI
50
Trexquant Investment
Connecticut
$2.85M -$2.06M -52,969 -47%