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AnaptysBio
ANAB

Overview Fund Activity

153 hedge funds and large institutions have $743M invested in AnaptysBio in 2025 Q1 according to their latest regulatory filings, with 45 funds opening new positions, 44 increasing their positions, 43 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
153
Holders Change
+18
Holders Change %
+13.33%
% of All Funds
2.08%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.07%
New
45
Increased
44
Reduced
43
Closed
26
Calls
$5.68M
Puts
$5.12M
Net Calls
+$558K
Net Calls Change
+$13.9M

Top Buyers

1
FLAM
First Light Asset Management
Minnesota
+$70M
2
Point72 Asset Management
Point72 Asset Management
Connecticut
+$44M
3
Bank of America
Bank of America
North Carolina
+$20.9M
4
SI
Sofinnova Investments
California
+$19.1M
5
Citigroup
Citigroup
New York
+$18.9M

Top Sellers

1
FFM
Fairmount Funds Management
Pennsylvania
-$24.1M
2
Fidelity Investments
Fidelity Investments
Massachusetts
-$20.9M
3
FLSM
Frazier Life Sciences Management
California
-$20.8M
4
CCM
Camber Capital Management
Massachusetts
-$9.3M
5
State Street
State Street
Massachusetts
-$7.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
Goldman Sachs
26
Goldman Sachs
New York
$5.22M -$2.58M -138,529 -33%
Two Sigma Advisers
27
Two Sigma Advisers
New York
$4.98M -$468K -25,200 -9%
Two Sigma Investments
28
Two Sigma Investments
New York
$4.94M -$1.6M -86,176 -24%
OM
29
Opaleye Management
Massachusetts
$4.66M +$4.66M +250,933 New
Assenagon Asset Management
30
Assenagon Asset Management
Luxembourg
$4.51M -$1.66M -89,273 -27%
Ensign Peak Advisors
31
Ensign Peak Advisors
Utah
$4.01M – – –
Northern Trust
32
Northern Trust
Illinois
$3.96M -$132K -7,100 -3%
6CM
33
683 Capital Management
New York
$3.64M +$3.64M +195,627 New
TI
34
Trexquant Investment
Connecticut
$2.85M +$1.73M +92,843 +153%
Charles Schwab
35
Charles Schwab
California
$2.85M -$236K -12,698 -8%
GIM
36
Granahan Investment Management
Massachusetts
$2.72M +$751K +40,412 +38%
D.E. Shaw & Co
37
D.E. Shaw & Co
New York
$2.41M -$1.25M -67,453 -34%
EAM
38
Exome Asset Management
New York
$2.17M +$2.17M +116,623 New
SCM
39
Soleus Capital Management
Connecticut
$1.9M -$5.8M -311,948 -75%
VOYA Investment Management
40
VOYA Investment Management
Georgia
$1.8M +$1.8M +96,972 New
Macquarie Group
41
Macquarie Group
Australia
$1.74M – – –
Marshall Wace
42
Marshall Wace
United Kingdom
$1.73M +$1.73M +92,870 New
HWM
43
HighMark Wealth Management
Minnesota
$1.71M +$1.71M +92,000 New
MAP
44
Moody Aldrich Partners
Massachusetts
$1.55M +$1.55M +83,224 New
Wellington Management Group
45
Wellington Management Group
Massachusetts
$1.41M +$178K +9,554 +14%
Bank of New York Mellon
46
Bank of New York Mellon
New York
$1.14M +$75.1K +4,038 +7%
Fisher Asset Management
47
Fisher Asset Management
Washington
$1.09M – – –
SC
48
SummitTX Capital
Texas
$1.06M +$1.06M +57,109 New
Barclays
49
Barclays
United Kingdom
$1.05M -$509K -27,348 -33%
NL
50
Nuveen LLC
North Carolina
$1.04M +$1.04M +56,012 New
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