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ALPN

Alpine Immune Sciences Inc
ALPN

Delisted

ALPN was delisted on the 17th of May, 2024.

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47 hedge funds and large institutions have $118M invested in Alpine Immune Sciences Inc in 2021 Q2 according to their latest regulatory filings, with 15 funds opening new positions, 8 increasing their positions, 14 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed

6% less first-time investments, than exits

New positions opened: 15 | Existing positions closed: 16

2% less funds holding

Funds holding: 48 → 47 (-1)

18% less capital invested

Capital invested by funds: $145M → $118M (-$26.6M)

43% less repeat investments, than reductions

Existing positions increased: 8 | Existing positions reduced: 14

Holders
47
Holders Change
-1
Holders Change %
-2.08%
% of All Funds
0.82%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
15
Increased
8
Reduced
14
Closed
16
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

Rank Fund Capital Flow
1
BlackRock
BlackRock
New York
+$5.62M
2
State Street
State Street
Massachusetts
+$1.88M
3
BCM
Bridgeway Capital Management
Texas
+$1.67M
4
Geode Capital Management
Geode Capital Management
Massachusetts
+$1.08M
5
Northern Trust
Northern Trust
Illinois
+$1.02M

Top Sellers

Rank Fund Capital Flow
1
SCM
Soleus Capital Management
Connecticut
-$3.32M
2
EC
EcoR1 Capital
California
-$2.38M
3
SFM
Sphera Funds Management
Israel
-$2.1M
4
OM
Opaleye Management
Massachusetts
-$1.66M
5
PVI
Pura Vida Investments
New York
-$1.4M
Name Holding Trade Value Shares
Change 		Change in
Stake
O
1
OrbiMed
New York
$27.6M – – –
FM
2
Frazier Management
Washington
$23.1M – – –
APM
3
Avidity Partners Management
Texas
$13.5M -$174K -16,000 -1%
OFM
4
Omega Fund Management
Massachusetts
$11.6M – – –
AG
5
Artal Group
Luxembourg
$5.34M – – –
Vanguard Group
6
Vanguard Group
Pennsylvania
$5.18M -$1.37K -126 -0%
BlackRock
7
BlackRock
New York
$4.9M +$5.62M +517,399 +1,934%
EC
8
EcoR1 Capital
California
$4.7M -$2.38M -218,655 -29%
Renaissance Technologies
9
Renaissance Technologies
New York
$3.59M +$22.8K +2,100 +0.5%
IC
10
Ikarian Capital
Texas
$2.7M -$46.6K -4,285 -1%
SB
11
Samsara BioCapital
California
$2.48M -$1.35M -124,021 -31%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$1.72M +$1.08M +99,396 +108%
State Street
13
State Street
Massachusetts
$1.56M +$1.88M +173,119 New
BCM
14
Bridgeway Capital Management
Texas
$1.38M +$1.67M +153,611 New
TM
15
Tiger Management
New York
$1.24M – – –
Deutsche Bank
16
Deutsche Bank
Germany
$1.21M -$1.2M -110,275 -45%
Northern Trust
17
Northern Trust
Illinois
$1.02M +$1.02M +93,666 +470%
DCM
18
DAFNA Capital Management
California
$1.02M – – –
Two Sigma Advisers
19
Two Sigma Advisers
New York
$623K -$617K -56,800 -45%
Acadian Asset Management
20
Acadian Asset Management
Massachusetts
$604K +$202K +18,615 +38%
Ensign Peak Advisors
21
Ensign Peak Advisors
Utah
$491K – – –
Dimensional Fund Advisors
22
Dimensional Fund Advisors
Texas
$408K – – –
Bank of New York Mellon
23
Bank of New York Mellon
New York
$377K +$208K +19,178 +85%
BFM
24
Boothbay Fund Management
New York
$320K -$13.8K -1,268 -3%
AA
25
ALPS Advisors
Colorado
$283K +$342K +31,498 New
1
2 3

ALPN Hedge Fund Activity: Q2 2021 in Review

47 of the 5,745 institutional investors tracked by Wall St. Rank reported a position in Alpine Immune Sciences Inc (ALPN) for Q2 2021, worth a combined $118M — down 18% from $145M a quarter earlier.

Sellers outnumbered buyers: 16 funds closed out of ALPN and 15 opened new positions — a net loss of 1 holder — while 14 trimmed existing stakes and 8 added.

The largest buyer was BlackRock, adding an estimated $5.62M. The largest seller was Soleus Capital Management, exiting entirely with an estimated $3.32M sold.

  • 47 institutional investors held Alpine Immune Sciences Inc (ALPN) as of Q2 2021, down from 48 in Q1 2021.
  • Funds reported $118M of Alpine Immune Sciences Inc stock for Q2 2021, down 18% quarter-over-quarter.
  • 15 funds opened new Alpine Immune Sciences Inc positions in Q2 2021 and 16 closed out, a net change of -1 holder.
  • The largest Alpine Immune Sciences Inc buyer in Q2 2021 was BlackRock, an estimated $5.62M added.
  • The largest Alpine Immune Sciences Inc seller in Q2 2021 was Soleus Capital Management, an estimated $3.32M sold.

Based on aggregated 13F filings for Q2 2021.