ALPN

Alpine Immune Sciences, Inc. Common Stock
ALPN

Overview Fund Activity
Delisted

ALPN was delisted on the 17th of May, 2024.

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48 hedge funds and large institutions have $145M invested in Alpine Immune Sciences, Inc. Common Stock in 2021 Q1 according to their latest regulatory filings, with 11 funds opening new positions, 15 increasing their positions, 10 reducing their positions, and 7 closing their positions.

Holders
48
Holders Change
+4
Holders Change %
+9.09%
% of All Funds
0.85%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
11
Increased
15
Reduced
10
Closed
7
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
IC
1
Ikarian Capital
Texas
$3.23M
2
SCM
2
Soleus Capital Management
Connecticut
$3.32M
3
APM
3
Avidity Partners Management
Texas
$16M
4
Deutsche Bank
4
Deutsche Bank
Germany
$2.59M
5
OM
5
Opaleye Management
Massachusetts
$1.66M

Top Sellers

1
Morgan Stanley
1
Morgan Stanley
New York
$57K
2
FCM
2
Farallon Capital Management
California
$0
3
CCM
3
CAAS Capital Management
New York
$0
4
EI
4
EAM Investors
California
$0
5
Renaissance Technologies
5
Renaissance Technologies
New York
$4.21M
Name Market Value Shares Shares
Change 		Shares
Change %
O
1
OrbiMed
New York
$32.6M 3,070,955 – –
FM
2
Frazier Management
Washington
$27.3M 2,571,450 – –
APM
3
Avidity Partners Management
Texas
$16M 1,511,000 +263,000 +21%
OFM
4
Omega Fund Management
Massachusetts
$13.6M 1,284,900 – –
EC
5
EcoR1 Capital
California
$7.86M 741,290 – –
AG
6
Artal Group
Luxembourg
$6.29M 593,030 – –
Vanguard Group
7
Vanguard Group
Pennsylvania
$6.1M 575,343 +27,700 +5%
SB
8
Samsara BioCapital
California
$4.23M 399,190 – –
Renaissance Technologies
9
Renaissance Technologies
New York
$4.21M 396,894 -61,900 -13%
SCM
10
Soleus Capital Management
Connecticut
$3.32M 313,064 +272,000 +662%
IC
11
Ikarian Capital
Texas
$3.23M 304,739 +300,000 +6,330%
Deutsche Bank
12
Deutsche Bank
Germany
$2.59M 244,332 +244,332 New
SFM
13
Sphera Funds Management
Israel
$2.1M 198,260 – –
OM
14
Opaleye Management
Massachusetts
$1.66M 156,500 +156,500 New
TM
15
Tiger Management
New York
$1.46M 137,728 – –
PVI
16
Pura Vida Investments
New York
$1.4M 131,981 -5,127 -4%
Two Sigma Advisers
17
Two Sigma Advisers
New York
$1.34M 125,975 +23,200 +23%
DCM
18
DAFNA Capital Management
California
$1.2M 113,302 +100 +0.1%
Two Sigma Investments
19
Two Sigma Investments
New York
$1.14M 107,381 -41,062 -28%
Millennium Management
20
Millennium Management
New York
$1.02M 96,017 +50,246 +110%
Geode Capital Management
21
Geode Capital Management
Massachusetts
$976K 92,142 +14,915 +19%
Susquehanna International Group
22
Susquehanna International Group
Pennsylvania
$633K 59,728 +59,728 New
Ensign Peak Advisors
23
Ensign Peak Advisors
Utah
$579K 54,580 +18,505 +51%
Acadian Asset Management
24
Acadian Asset Management
Massachusetts
$515K 48,541 +45,898 +1,737%
Dimensional Fund Advisors
25
Dimensional Fund Advisors
Texas
$480K 45,300 -2,854 -6%
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