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ALPN

Alpine Immune Sciences Inc

Delisted

ALPN was delisted on the 17th of May, 2024.

44 hedge funds and large institutions have $160M invested in Alpine Immune Sciences Inc in 2020 Q4 according to their latest regulatory filings, with 11 funds opening new positions, 13 increasing their positions, 8 reducing their positions, and 2 closing their positions.

New
Increased
Maintained
Reduced
Closed

450% more first-time investments, than exits

New positions opened: 11 | Existing positions closed: 2

63% more repeat investments, than reductions

Existing positions increased: 13 | Existing positions reduced: 8

46% more capital invested

Capital invested by funds: $110M → $160M (+$50.5M)

26% more funds holding

Funds holding: 3544 (+9)

100% less funds holding in top 10

Funds holding in top 10: 10 (-1)

Holders
44
Holders Change
+9
Holders Change %
+25.71%
% of All Funds
0.78%
Holding in Top 10
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
New
11
Increased
13
Reduced
8
Closed
2
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
O
1
OrbiMed
New York
$38.7M -$5.89M -600,000 -16%
FM
2
Frazier Management
Washington
$32.4M
OFM
3
Omega Fund Management
Massachusetts
$16.2M
APM
4
Avidity Partners Management
Texas
$15.7M +$4.3M +438,000 +54%
EC
5
EcoR1 Capital
California
$9.34M
AG
6
Artal Group
Luxembourg
$7.47M
Vanguard Group
7
Vanguard Group
Pennsylvania
$6.9M +$2.26M +230,752 +73%
Renaissance Technologies
8
Renaissance Technologies
New York
$5.78M +$688K +70,111 +18%
Morgan Stanley
9
Morgan Stanley
New York
$4.76M +$3.68M +375,306 +15,528%
FCM
10
Farallon Capital Management
California
$2.52M -$5.31M -541,290 -73%
SFM
11
Sphera Funds Management
Israel
$2.5M
Two Sigma Investments
12
Two Sigma Investments
New York
$1.87M +$658K +67,078 +82%
CCM
13
CAAS Capital Management
New York
$1.87M +$1.45M +148,200 New
TM
14
Tiger Management
New York
$1.74M
PVI
15
Pura Vida Investments
New York
$1.73M +$1.35M +137,108 New
DCM
16
DAFNA Capital Management
California
$1.43M -$344K -35,058 -24%
Two Sigma Advisers
17
Two Sigma Advisers
New York
$1.29M +$288K +29,300 +40%
ECM
18
ExodusPoint Capital Management
New York
$1.14M +$886K +90,229 New
Geode Capital Management
19
Geode Capital Management
Massachusetts
$973K +$296K +30,145 +64%
EI
20
EAM Investors
California
$797K +$621K +63,261 New
Dimensional Fund Advisors
21
Dimensional Fund Advisors
Texas
$607K
Qube Research & Technologies (QRT)
22
Qube Research & Technologies (QRT)
United Kingdom
$587K +$90.1K +9,179 +25%
Millennium Management
23
Millennium Management
New York
$577K -$2.82K -287 -0.6%
SCM
24
Soleus Capital Management
Connecticut
$517K +$403K +41,064 New
Ensign Peak Advisors
25
Ensign Peak Advisors
Utah
$455K +$354K +36,075 New

ALPN Hedge Fund Activity: Q4 2020 in Review

44 of the 5,651 institutional investors tracked by Wall St. Rank reported a position in Alpine Immune Sciences Inc (ALPN) for Q4 2020, worth a combined $160M — up 46% from $110M a quarter earlier.

Buyers outnumbered sellers: 11 funds opened new ALPN positions and 2 closed out — a net gain of 9 holders — while 13 added to existing stakes and 8 trimmed.

The largest buyer was Avidity Partners Management, adding an estimated $4.3M. The largest seller was OrbiMed, cutting an estimated $5.89M.

  • 44 institutional investors held Alpine Immune Sciences Inc (ALPN) as of Q4 2020, up from 35 in Q3 2020.
  • Funds reported $160M of Alpine Immune Sciences Inc stock for Q4 2020, up 46% quarter-over-quarter.
  • 11 funds opened new Alpine Immune Sciences Inc positions in Q4 2020 and 2 closed out, a net change of +9 holders.
  • The largest Alpine Immune Sciences Inc buyer in Q4 2020 was Avidity Partners Management, an estimated $4.3M added.
  • The largest Alpine Immune Sciences Inc seller in Q4 2020 was OrbiMed, an estimated $5.89M sold.

Based on aggregated 13F filings for Q4 2020.