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Alnylam Pharmaceuticals

833 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 284 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.56B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
833
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
HWP
776
Highline Wealth Partners
California
$3.18K
SRCM
777
Signature Resources Capital Management
California
$3.18K
PCM
778
Penserra Capital Management
California
$3K
JFGIW
779
Johnson Financial Group Inc (Wisconsin)
Wisconsin
$2.78K
FRA
780
Front Row Advisors
California
$2.78K
CHC
781
City Holding Co
West Virginia
$2.78K
AF
782
Advisornet Financial
Minnesota
$2.39K
PWA
783
Principia Wealth Advisory
Texas
$2.39K
SEP
784
Signature Equity Partners
Ohio
$2.39K
EWP
785
Elevation Wealth Partners
California
$2.39K
ANBT
786
American National Bank & Trust
Texas
$2.39K
SGK
787
Steigerwald Gordon & Koch
Virginia
$2.39K
WCM
788
Winthrop Capital Management
Indiana
$2K
CI
789
CX Institutional
Indiana
$2K
ADL
790
Asset Dedication LLC
California
$1.99K
CIAS
791
CBIZ Investment Advisory Services
Ohio
$1.99K
NRG
792
Nemes Rush Group
Michigan
$1.99K
OC
793
Optima Capital
Oregon
$1.99K
HNW
794
High Note Wealth
Minnesota
$1.99K
LWM
795
Lodestone Wealth Management
Washington
$1.99K
DF
796
Dunhill Financial
United Kingdom
$1.99K
MA
797
Montag & Associates
Georgia
$1.86K
AWM
798
Abound Wealth Management
Tennessee
$1.73K
WW
799
Winnow Wealth
Texas
$1.59K
BHWM
800
Beaird Harris Wealth Management
Texas
$1.59K