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Alnylam Pharmaceuticals

833 hedge funds and large institutions have $51.6B invested in Alnylam Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 160 funds opening new positions, 284 increasing their positions, 290 reducing their positions, and 115 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more first-time investments, than exits

New positions opened: | Existing positions closed:

more funds holding

Funds holding:

less ownership

Funds ownership:

2% less repeat investments, than reductions

Existing positions increased: 284 | Existing positions reduced: 290

13% less capital invested

Capital invested by funds: $59.2B → $51.6B (-$7.56B)

69% less funds holding in top 10

Funds holding in top 10: 134 (-9)

Holders
833
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
4
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$760M
Puts
$448M
Net Calls
Net Calls Change

Top Buyers

1 +$303M
2 +$220M
3 +$158M
4
UBS Group
UBS Group
Switzerland
+$149M
5
D.E. Shaw & Co
D.E. Shaw & Co
New York
+$108M

Top Sellers

1 -$635M
2 -$383M
3 -$360M
4
Jane Street
Jane Street
New York
-$287M
5
Macquarie Group
Macquarie Group
Australia
-$276M
Name Holding Trade Value Shares
Change
Change in
Stake
TCOV
751
Trust Company of Vermont
Vermont
$5.57K
UB
752
UMB Bank
Missouri
$5.57K
HWM
753
HighMark Wealth Management
Minnesota
$5.57K
CWIG
754
Chung Wu Investment Group
Texas
$5.17K
M
755
MOTCO
Texas
$5.17K
CFM
756
Cornerstone Financial Management
Massachusetts
$5.17K
VNA
757
Valley National Advisers
Pennsylvania
$5K
ACM
758
Accent Capital Management
Ohio
$4.77K
HFS
759
Hughes Financial Services
Virginia
$4.77K
STB
760
S&T Bank
Pennsylvania
$4.37K
FHA
761
Flagship Harbor Advisors
Massachusetts
$4.37K
CW
762
Curio Wealth
Maryland
$4.01K
MSFP
763
Mark Sheptoff Financial Planning
Connecticut
$3.98K
AIC
764
Archer Investment Corporation
Indiana
$3.98K
TWM
765
Tripletail Wealth Management
Florida
$3.98K
TFA
766
Toth Financial Advisory
Virginia
$3.98K
HIA
767
HFM Investment Advisors
New Jersey
$3.98K
HPWM
768
High Point Wealth Management
New Jersey
$3.98K
AG
769
AmeriFlex Group
Nevada
$3.58K
GBT
770
Grove Bank & Trust
Florida
$3.58K
BHWM
771
Bay Harbor Wealth Management
Maryland
$3.58K
WTA
772
Washington Trust Advisors
Massachusetts
$3.42K
DPW
773
DiNuzzo Private Wealth
Pennsylvania
$3.18K
FPF
774
First Pacific Financial
Washington
$3.18K
NS
775
NBC Securities
Alabama
$3.18K