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Alnylam Pharmaceuticals

784 hedge funds and large institutions have $40.1B invested in Alnylam Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 87 funds opening new positions, 319 increasing their positions, 280 reducing their positions, and 80 closing their positions.

New
Increased
Maintained
Reduced
Closed

113% more call options, than puts

Call options by funds: $453M | Put options by funds: $213M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

14% more repeat investments, than reductions

Existing positions increased: 319 | Existing positions reduced: 280

9% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 80

0.64% more ownership

Funds ownership: 99.08%99.72% (+0.64%)

1% less funds holding

Funds holding: 791784 (-7)

8% less capital invested

Capital invested by funds: $43.4B → $40.1B (-$3.32B)

Holders
784
Holders Change
-7
Holders Change %
-0.88%
% of All Funds
9.47%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
87
Increased
319
Reduced
280
Closed
80
Calls
$453M
Puts
$213M
Net Calls
+$240M
Net Calls Change
-$5M
Name Holding Trade Value Shares
Change
Change in
Stake
Sumitomo Mitsui Trust Group
51
Sumitomo Mitsui Trust Group
Japan
$97.9M +$3.31M +10,962 +3%
Millennium Management
52
Millennium Management
New York
$95.1M -$39.8M -131,886 -29%
Nuveen
53
Nuveen
North Carolina
$95M -$1.99M -6,602 -2%
CS
54
Candriam SCA
Luxembourg
$94.6M +$27.2M +90,182 +40%
Wells Fargo
55
Wells Fargo
California
$93.3M -$9.87M -32,716 -10%
NAMI
56
Nomura Asset Management International
Pennsylvania
$90.4M +$12.5M +41,288 +16%
Susquehanna International Group
57
Susquehanna International Group
Pennsylvania
$88.6M +$36.3M +120,192 +69%
Pictet Asset Management
58
Pictet Asset Management
Switzerland
$83.3M +$12.3M +40,693 +17%
BNP Paribas Financial Markets
59
BNP Paribas Financial Markets
France
$81.6M -$3M -9,942 -4%
GGHC
60
Gilder Gagnon Howe & Co
New York
$81M -$3.33M -11,041 -4%
CAM
61
Congress Asset Management
Massachusetts
$80M -$6.04M -20,038 -7%
Marshall Wace
62
Marshall Wace
United Kingdom
$78.2M -$253M -839,519 -76%
Vanguard Asset Management
63
Vanguard Asset Management
$77.6M +$11.6M +38,475 +18%
California Public Employees Retirement System
64
California Public Employees Retirement System
California
$76.5M +$7.86M +26,056 +11%
Westfield Capital Management
65
Westfield Capital Management
Massachusetts
$76M +$2.06M +6,844 +3%
Korea Investment Corp
66
Korea Investment Corp
South Korea
$74.6M +$14.3M +47,339 +24%
WP
67
Woodline Partners
California
$74.1M +$724K +2,399 +1%
Squarepoint
68
Squarepoint
New York
$70.4M -$58.1M -192,724 -45%
TD Asset Management
69
TD Asset Management
Ontario, Canada
$70.3M -$14.5M -48,152 -17%
Citigroup
70
Citigroup
New York
$68.6M -$10.7M -35,589 -14%
Royal London Asset Management
71
Royal London Asset Management
United Kingdom
$64.3M -$448K -1,486 -0.7%
Ameriprise
72
Ameriprise
Minnesota
$61.6M -$10.7M -35,340 -15%
National Pension Service
73
National Pension Service
South Korea
$59.7M +$4.38M +14,506 +8%
PI
74
PineBridge Investments
New York
$58.9M -$22.8M -75,710 -28%
Citadel Advisors
75
Citadel Advisors
Florida
$57.5M +$50.6M +167,614 +716%

ALNY Hedge Fund Activity: Q2 2026 in Review

784 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Alnylam Pharmaceuticals (ALNY) for Q2 2026, worth a combined $40.1B — down 7.7% from $43.4B a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new ALNY positions and 80 closed out — a net gain of 7 holders — while 319 added to existing stakes and 280 trimmed.

The largest buyer was Deep Track Capital, opening a new position worth an estimated $249M. The largest seller was JP Morgan Chase, cutting an estimated $1.1B.

  • 784 institutional investors held Alnylam Pharmaceuticals (ALNY) as of Q2 2026, down from 791 in Q1 2026.
  • Funds reported $40.1B of Alnylam Pharmaceuticals stock for Q2 2026, down 7.7% quarter-over-quarter.
  • 87 funds opened new Alnylam Pharmaceuticals positions in Q2 2026 and 80 closed out, a net change of +7 holders.
  • The largest Alnylam Pharmaceuticals buyer in Q2 2026 was Deep Track Capital, an estimated $249M added.
  • The largest Alnylam Pharmaceuticals seller in Q2 2026 was JP Morgan Chase, an estimated $1.1B sold.

Based on aggregated 13F filings for Q2 2026.