We are live on ! Find out more
ALNY icon

Alnylam Pharmaceuticals

784 hedge funds and large institutions have $40.1B invested in Alnylam Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 87 funds opening new positions, 319 increasing their positions, 280 reducing their positions, and 80 closing their positions.

New
Increased
Maintained
Reduced
Closed

113% more call options, than puts

Call options by funds: $453M | Put options by funds: $213M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

14% more repeat investments, than reductions

Existing positions increased: 319 | Existing positions reduced: 280

9% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 80

0.64% more ownership

Funds ownership: 99.08%99.72% (+0.64%)

1% less funds holding

Funds holding: 791784 (-7)

8% less capital invested

Capital invested by funds: $43.4B → $40.1B (-$3.32B)

Holders
784
Holders Change
-7
Holders Change %
-0.88%
% of All Funds
9.47%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
87
Increased
319
Reduced
280
Closed
80
Calls
$453M
Puts
$213M
Net Calls
+$240M
Net Calls Change
-$5M
Name Holding Trade Value Shares
Change
Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$267M +$8.68M +28,780 +3%
Royal Bank of Canada
27
Royal Bank of Canada
Ontario, Canada
$264M +$25.4M +84,344 +11%
Vanguard Fiduciary Trust
28
Vanguard Fiduciary Trust
Pennsylvania
$260M +$6.6M +21,894 +3%
DTC
29
Deep Track Capital
Connecticut
$248M +$249M +825,000 New
Deutsche Bank
30
Deutsche Bank
Germany
$245M +$16.3M +53,936 +7%
Qube Research & Technologies (QRT)
31
Qube Research & Technologies (QRT)
United Kingdom
$240M -$11.9M -39,472 -5%
Charles Schwab
32
Charles Schwab
California
$227M +$24.7M +82,021 +12%
Los Angeles Capital Management
33
Los Angeles Capital Management
California
$220M +$193M +641,357 +727%
UBS AM
34
UBS AM
Illinois
$219M +$15.2M +50,329 +7%
AQR Capital Management
35
AQR Capital Management
Connecticut
$219M -$55.8M -185,065 -20%
Federated Hermes
36
Federated Hermes
Pennsylvania
$217M +$9.68M +32,089 +5%
UBS Group
37
UBS Group
Switzerland
$189M +$50.7M +168,134 +37%
Amundi
38
Amundi
France
$186M -$39.2M -130,073 -17%
Loomis, Sayles & Company
39
Loomis, Sayles & Company
Massachusetts
$175M +$20.5M +68,090 +13%
Goldman Sachs
40
Goldman Sachs
New York
$173M +$31.8M +105,369 +22%
Bank of New York Mellon
41
Bank of New York Mellon
New York
$148M +$263K +871 +0.2%
PCH
42
Polar Capital Holdings
United Kingdom
$145M +$67.9M +225,077 +87%
PBA
43
Paradigm Biocapital Advisors
New York
$144M +$145M +480,000 New
Franklin Resources
44
Franklin Resources
California
$135M -$6.84M -22,691 -5%
First Trust Advisors
45
First Trust Advisors
Illinois
$127M +$11.7M +38,833 +10%
Raymond James Financial
46
Raymond James Financial
Florida
$118M -$4.27M -14,157 -3%
Dimensional Fund Advisors
47
Dimensional Fund Advisors
Texas
$118M +$2.36M +7,817 +2%
Swiss National Bank
48
Swiss National Bank
Switzerland
$113M -$4.11M -13,640 -4%
Massachusetts Financial Services
49
Massachusetts Financial Services
Massachusetts
$106M -$43.9M -145,444 -29%
Canada Pension Plan Investment Board
50
Canada Pension Plan Investment Board
Ontario, Canada
$101M +$37.8M +125,308 +60%

ALNY Hedge Fund Activity: Q2 2026 in Review

784 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Alnylam Pharmaceuticals (ALNY) for Q2 2026, worth a combined $40.1B — down 7.7% from $43.4B a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new ALNY positions and 80 closed out — a net gain of 7 holders — while 319 added to existing stakes and 280 trimmed.

The largest buyer was Deep Track Capital, opening a new position worth an estimated $249M. The largest seller was JP Morgan Chase, cutting an estimated $1.1B.

  • 784 institutional investors held Alnylam Pharmaceuticals (ALNY) as of Q2 2026, down from 791 in Q1 2026.
  • Funds reported $40.1B of Alnylam Pharmaceuticals stock for Q2 2026, down 7.7% quarter-over-quarter.
  • 87 funds opened new Alnylam Pharmaceuticals positions in Q2 2026 and 80 closed out, a net change of +7 holders.
  • The largest Alnylam Pharmaceuticals buyer in Q2 2026 was Deep Track Capital, an estimated $249M added.
  • The largest Alnylam Pharmaceuticals seller in Q2 2026 was JP Morgan Chase, an estimated $1.1B sold.

Based on aggregated 13F filings for Q2 2026.