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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

640 hedge funds and large institutions have $42.9B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 96 funds opening new positions, 253 increasing their positions, 213 reducing their positions, and 63 closing their positions.

Holders
640
Holders Change
+22
Holders Change %
+3.56%
% of All Funds
8.6%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
96
Increased
253
Reduced
213
Closed
63
Calls
$122M
Puts
$147M
Net Calls
-$25M
Net Calls Change
-$60.4M

Top Buyers

1
Norges Bank
1
Norges Bank
Norway
$663M
2
Citadel Advisors
2
Citadel Advisors
Florida
$196M
3
Holocene Advisors
3
Holocene Advisors
New York
$195M
4
ClearBridge Investments
4
ClearBridge Investments
New York
$182M
5
Macquarie Group
5
Macquarie Group
Australia
$196M

Top Sellers

1
AQR Capital Management
1
AQR Capital Management
Connecticut
$61.3M
2
Baillie Gifford & Co
2
Baillie Gifford & Co
United Kingdom
$989M
3
Wellington Management Group
3
Wellington Management Group
Massachusetts
$677M
4
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$1.03B
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$0
Name Market Value Shares Shares
Change 		Shares
Change %
BG
26
Bellevue Group
Switzerland
$221M 676,367 -91,780 -12%
Deutsche Bank
27
Deutsche Bank
Germany
$212M 649,284 +72,291 +13%
WP
28
Woodline Partners
California
$203M 623,115 +466,651 +298%
Franklin Resources
29
Franklin Resources
California
$196M 601,331 +143,017 +31%
Citadel Advisors
30
Citadel Advisors
Florida
$196M 601,199 +596,963 +14,093%
Macquarie Group
31
Macquarie Group
Australia
$196M 600,111 +527,519 +727%
Holocene Advisors
32
Holocene Advisors
New York
$195M 596,816 +596,816 New
Charles Schwab
33
Charles Schwab
California
$186M 571,747 +17,141 +3%
ClearBridge Investments
34
ClearBridge Investments
New York
$182M 557,099 +549,322 +7,063%
Goldman Sachs
35
Goldman Sachs
New York
$178M 545,316 +121,949 +29%
UBS Group
36
UBS Group
Switzerland
$177M 543,486 +264,848 +95%
Loomis, Sayles & Company
37
Loomis, Sayles & Company
Massachusetts
$159M 487,328 -10,156 -2%
Pictet Asset Management
38
Pictet Asset Management
Switzerland
$151M 464,606 -16,361 -3%
TD Asset Management
39
TD Asset Management
Ontario, Canada
$144M 441,177 -45,407 -9%
Royal Bank of Canada
40
Royal Bank of Canada
Ontario, Canada
$140M 430,835 +93,604 +28%
Bank of New York Mellon
41
Bank of New York Mellon
New York
$140M 429,769 -45,063 -9%
Amundi
42
Amundi
France
$130M 394,179 -60,816 -13%
Swiss National Bank
43
Swiss National Bank
Switzerland
$128M 393,800 +29,600 +8%
Jennison Associates
44
Jennison Associates
New York
$114M 350,070 +40,851 +13%
Two Sigma Investments
45
Two Sigma Investments
New York
$112M 343,305 +145,890 +74%
O
46
OrbiMed
New York
$111M 341,900 -4,200 -1%
GGHC
47
Gilder Gagnon Howe & Co
New York
$110M 337,088 -8,487 -2%
Federated Hermes
48
Federated Hermes
Pennsylvania
$106M 323,842 +59,669 +23%
Wells Fargo
49
Wells Fargo
California
$105M 321,824 +21,744 +7%
SEI Investments
50
SEI Investments
Pennsylvania
$101M 308,619 +31,250 +11%
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