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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
$196M
2
Holocene Advisors
Holocene Advisors
New York
$195M
3
ClearBridge Investments
ClearBridge Investments
New York
$182M
4
Macquarie Group
Macquarie Group
Australia
$196M
5
Fidelity Investments
Fidelity Investments
Massachusetts
$5.15B

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
$61.3M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$989M
3
Wellington Management Group
Wellington Management Group
Massachusetts
$677M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$1.03B
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
BM
651
Bridger Management
New York
– -$9.44M -34,975 Closed
MIF
652
Mediolanum International Funds
Ireland
– -$9.32M -34,729 Closed
AIMCA
653
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
– -$4.78M -17,700 Closed
ACM
654
Aquatic Capital Management
Illinois
– -$3.87M -14,348 Closed
DP
655
Diadema Partners
New Jersey
– -$3.54M -13,115 Closed
SCM
656
Suvretta Capital Management
New York
– -$2.53M -9,370 Closed
LP
657
LMR Partners
United Kingdom
– -$2.43M -9,000 Closed
FC
658
FORA Capital
Florida
– -$2.33M -8,624 Closed
SP
659
SIH Partners
Delaware
– -$2.15M -7,959 Closed
Twin Tree Management
660
Twin Tree Management
Texas
– -$1.91M -7,074 Closed
Simplex Trading
661
Simplex Trading
Illinois
– -$1.81M -6,704 Closed
PFM
662
Privium Fund Management
Netherlands
– -$1.54M -5,716 Closed
PCM
663
Prelude Capital Management
New York
– -$1.46M -5,408 Closed
DFCM
664
Dark Forest Capital Management
Puerto Rico
– -$1.39M -5,153 Closed
AC
665
Allstate Corporation
Illinois
– -$1.27M -4,701 Closed
MWVC
666
Morgens Waterfall Vintiadis & Co
New York
– -$1.08M -4,000 Closed
PHK
667
Point72 Hong Kong
Hong Kong
– -$1.02M -3,795 Closed
YIH
668
Y-Intercept (HK)
Hong Kong
– -$1M -3,720 Closed
PL
669
Perpetual Ltd
Australia
– -$1M -3,718 Closed
SMH
670
Sanders Morris Harris
Texas
– -$895K -3,500 Closed
SGI
671
Summit Global Investments
Utah
– -$849K -3,145 Closed
PAP
672
Persistent Asset Partners
Hong Kong
– -$819K -3,034 Closed
AWM
673
Accurate Wealth Management
Florida
– -$590K -2,483 Closed
ACM
674
Aster Capital Management
United Arab Emirates
– -$605K -2,451 Closed
PEAK6
675
PEAK6
Illinois
– -$620K -2,295 Closed
25 26
27
28 29