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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
$196M
2
Holocene Advisors
Holocene Advisors
New York
$195M
3
ClearBridge Investments
ClearBridge Investments
New York
$182M
4
Macquarie Group
Macquarie Group
Australia
$196M
5
Fidelity Investments
Fidelity Investments
Massachusetts
$5.15B

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
$61.3M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$989M
3
Wellington Management Group
Wellington Management Group
Massachusetts
$677M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$1.03B
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
CIAS
626
CBIZ Investment Advisory Services
Ohio
$1.63K – – –
RFS
627
Richardson Financial Services
Massachusetts
$1.63K – – –
PWA
628
Principia Wealth Advisory
Texas
$1.63K +$652 +2 +67%
SIC
629
SJS Investment Consulting
Ohio
$1.31K -$979 -3 -43%
ACA
630
American Capital Advisory
Idaho
$1.31K +$1.31K +4 New
PWM
631
Parkworth Wealth Management
California
$1.3K +$652 +2 +100%
AWM
632
Abound Wealth Management
Tennessee
$979 – – –
MCM
633
Manchester Capital Management
Vermont
$979 +$326 +1 +50%
BHWM
634
Beaird Harris Wealth Management
Texas
$979 +$979 +3 New
RWM
635
Rialto Wealth Management
New York
$979 +$979 +3 New
AF
636
Advisornet Financial
Minnesota
$978 – – –
HIA
637
HFM Investment Advisors
New Jersey
$978 +$652 +2 +200%
RIL
638
Rothschild Investment LLC
Illinois
$652 -$326 -1 -33%
CA
639
CoreCap Advisors
Michigan
$652 – – –
LCM
640
Logan Capital Management
Pennsylvania
$652 – – –
QWM
641
Quaker Wealth Management
New Jersey
$327 +$327 +1 New
CFD
642
Creative Financial Designs
Indiana
$326 – – –
TPCW
643
TD Private Client Wealth
New York
$326 – – –
RJA
644
Ross\Johnson & Associates
Minnesota
$326 – – –
AWM
645
Activest Wealth Management
Florida
$326 +$326 +1 New
Qube Research & Technologies (QRT)
646
Qube Research & Technologies (QRT)
United Kingdom
– -$89.2M -330,347 Closed
SI
647
Sofinnova Investments
California
– -$47.6M -176,181 Closed
SG Americas Securities
648
SG Americas Securities
New York
– -$35.9M -132,960 Closed
JGC
649
J. Goldman & Co
New York
– -$20M -74,185 Closed
SFM
650
Soros Fund Management
New York
– -$16.2M -60,000 Closed
24 25
26
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