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Alnylam Pharmaceuticals

785 hedge funds and large institutions have $42.5B invested in Alnylam Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 102 funds opening new positions, 320 increasing their positions, 257 reducing their positions, and 153 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

18% less capital invested

Capital invested by funds: $51.7B → $42.5B (-$9.26B)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

33% less first-time investments, than exits

New positions opened: 102 | Existing positions closed: 153

Holders
785
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$450M
Puts
$205M
Net Calls
Net Calls Change

Top Buyers

1 +$1.17B
2 +$916M
3 +$546M
4
Two Sigma Investments
Two Sigma Investments
New York
+$468M
5
ClearBridge Investments
ClearBridge Investments
New York
+$258M

Top Sellers

1 -$1.87B
2 -$450M
3 -$448M
4
Invesco
Invesco
Georgia
-$297M
5
1832 Asset Management
1832 Asset Management
Ontario, Canada
-$175M
Name Holding Trade Value Shares
Change
Change in
Stake
HNWAG
476
High Net Worth Advisory Group
Florida
$496K
LWCFA
477
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$494K
RFC
478
Regions Financial Corp
Alabama
$487K
QI
479
Qtron Investments
Massachusetts
$487K
PR
480
PSP Research
Pennsylvania
$485K
SI
481
Stephens Inc
Arkansas
$471K
OF
482
Optimize Financial
California
$457K
AA
483
AlphaCentric Advisors
Puerto Rico
$453K
CCM
484
Coldstream Capital Management
Washington
$447K
WAP
485
Wealthcare Advisory Partners
Pennsylvania
$440K
FFS
486
Founders Financial Securities
Maryland
$437K
LJAC
487
L.J. Altfest & Co
New York
$436K
SAM
488
Smartleaf Asset Management
Massachusetts
$430K
CGH
489
Crossmark Global Holdings
Texas
$428K
IG
490
ING Group
Netherlands
$426K
SI
491
Sava Infond
Slovenia
$425K
AF
492
Allworth Financial
California
$425K
MYIA
493
Mount Yale Investment Advisors
Colorado
$418K
FRA
494
Frank Rimerman Advisors
California
$416K
SBFM
495
S-Bank Fund Management
Finland
$409K
DWM
496
Dynasty Wealth Management
Florida
$408K
CI
497
Cigna Investments
Connecticut
$407K
GIM
498
Generali Investments Management
Slovenia
$406K
MCM
499
MAI Capital Management
Ohio
$400K
WPC
500
Wedmont Private Capital
Pennsylvania
$400K