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Alnylam Pharmaceuticals

785 hedge funds and large institutions have $42.5B invested in Alnylam Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 102 funds opening new positions, 320 increasing their positions, 257 reducing their positions, and 153 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

18% less capital invested

Capital invested by funds: $51.7B → $42.5B (-$9.26B)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

33% less first-time investments, than exits

New positions opened: 102 | Existing positions closed: 153

Holders
785
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$450M
Puts
$205M
Net Calls
Net Calls Change

Top Buyers

1 +$1.17B
2 +$916M
3 +$546M
4
Two Sigma Investments
Two Sigma Investments
New York
+$468M
5
ClearBridge Investments
ClearBridge Investments
New York
+$258M

Top Sellers

1 -$1.87B
2 -$450M
3 -$448M
4
Invesco
Invesco
Georgia
-$297M
5
1832 Asset Management
1832 Asset Management
Ontario, Canada
-$175M
Name Holding Trade Value Shares
Change
Change in
Stake
HI
426
Horizon Investments
North Carolina
$871K
JSAM
427
J. Safra Asset Management
New York
$865K
SAM
428
Sectoral Asset Management
Quebec, Canada
$864K
UM
429
UniSuper Management
Australia
$827K
WBC
430
Westpac Banking Corp
Australia
$811K
CPBTD
431
Central Pacific Bank - Trust Division
Hawaii
$798K
CGIM
432
Cannon Global Investment Management
Florida
$794K
NPT
433
Nixon Peabody Trust
Massachusetts
$768K
NA
434
NewEdge Advisors
Louisiana
$766K
QCM
435
QRG Capital Management
Illinois
$754K
HKAM
436
Horizon Kinetics Asset Management
New York
$752K
GIA
437
Gateway Investment Advisers
Ohio
$745K
PCA
438
Pallas Capital Advisors
Massachusetts
$732K
IPAM
439
ICICI Prudential Asset Management
India
$727K
TG
440
TCW Group
California
$695K
S
441
SignatureFD
Georgia
$677K
ACS
442
Archford Capital Strategies
Illinois
$674K
HHGC
443
Hunting Hill Global Capital
New York
$673K
SNBOSD
444
Security National Bank of So Dak
Iowa
$662K
MG
445
Marex Group
$662K
HWM
446
HB Wealth Management
Georgia
$660K
Caisse de Depot et Placement du Quebec (CDPQ)
447
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$658K
TE
448
Tema ETFs
New York
$652K
VSQM
449
V-Square Quantitative Management
Illinois
$651K
Kovitz Investment Group Partners
450
Kovitz Investment Group Partners
Illinois
$648K