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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

617 hedge funds and large institutions have $34.2B invested in Alnylam Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 107 funds opening new positions, 236 increasing their positions, 197 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
617
Holders Change
+32
Holders Change %
+5.47%
% of All Funds
8.38%
Holding in Top 10
10
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+150%
% of All Funds
0.14%
New
107
Increased
236
Reduced
197
Closed
67
Calls
$274M
Puts
$238M
Net Calls
+$35.4M
Net Calls Change
+$6.38M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$493M
2
Bank of America
Bank of America
North Carolina
+$174M
3
Invesco
Invesco
Georgia
+$95.9M
4
Vanguard Group
Vanguard Group
Pennsylvania
+$87.3M
5
Point72 Asset Management
Point72 Asset Management
Connecticut
+$81.2M

Top Sellers

1
Wellington Management Group
Wellington Management Group
Massachusetts
-$428M
2
Capital International Investors
Capital International Investors
California
-$334M
3
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$103M
4
BlackRock
BlackRock
New York
-$88M
5
Corient Private Wealth
Corient Private Wealth
Florida
-$63.7M
Name Holding Trade Value Shares
Change 		Shares
Change %
AAIS
426
ABN AMRO Investment Solutions
$354K +$26.7K +99 +8%
NSAM
427
North Star Asset Management
Wisconsin
$352K -$1.35K -5 -0.4%
CA
428
Clearstead Advisors
Ohio
$352K +$52.4K +194 +17%
KRW
429
Kaufman Rossin Wealth
Florida
$351K +$351K +1,300 New
CI
430
Cigna Investments
Connecticut
$351K – – –
PMFA
431
Plante Moran Financial Advisors
Michigan
$347K +$176K +650 +102%
CWM
432
Crowley Wealth Management
Delaware
$338K – – –
PCM
433
Penserra Capital Management
California
$329K +$326K +1,208 +10,067%
OIA
434
OneDigital Investment Advisors
Kansas
$327K +$44.6K +165 +16%
BJL
435
Brighton Jones LLC
Washington
$326K +$47.8K +177 +17%
NAM
436
NorthCrest Asset Manangement
Minnesota
$323K +$323K +1,196 New
QCM
437
Qsemble Capital Management
New York
$323K +$323K +1,196 New
TFIPS
438
Towarzystwo Funduszy Inwestycyjnych PZU SA
$314K +$43.2K +160 +16%
TSS
439
Two Sigma Securities
New York
$313K +$11.3K +42 +4%
BTI
440
Blue Trust Inc
Georgia
$313K +$79.1K +293 +34%
AG
441
Algert Global
California
$311K +$311K +1,150 New
PCM
442
Peregrine Capital Management
Minnesota
$310K – – –
CBA
443
Coastal Bridge Advisors
Connecticut
$307K +$307K +1,136 New
WSFS
444
Wilmington Savings Fund Society
Delaware
$296K +$294K +1,089 +12,100%
CCM
445
Coldstream Capital Management
Washington
$291K -$9.18K -34 -3%
SPIA
446
Steward Partners Investment Advisory
New York
$287K +$32.9K +122 +13%
TC
447
TownSquare Capital
Utah
$286K +$25.1K +93 +10%
LJAC
448
L.J. Altfest & Co
New York
$284K +$284K +1,050 New
NPA
449
Nichols & Pratt Advisers
Massachusetts
$282K -$89.6K -332 -24%
PS
450
Principal Securities
Iowa
$279K – – –
16 17
18
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