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Two Sigma Securities’s Alnylam Pharmaceuticals ALNY Stock Holding History

Two Sigma Securities’s Portfolio ALNY Stock Details ALNY Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-1,740
Closed -$793K – 1444
2025
Q3 		$793K Buy
+1,740
New +$709K 0.12% 222
2025
Q2 		– Sell
-1,159
Closed -$313K – 1469
2025
Q1 		$313K Buy
1,159
+42
+4% +$10.8K 0.05% 567
2024
Q4 		$263K Buy
+1,117
New +$294K 0.03% 745
2024
Q3 		– Sell
-54,142
Closed -$14.1M – 2802
2024
Q2 		$13.2M Buy
+54,142
New +$8.55M 0.16% 152
2023
Q3 		– Sell
-5,111
Closed -$975K – 2893
2023
Q2 		$971K Buy
5,111
+3,590
+236% +$712K 0.01% 990
2023
Q1 		$305K Sell
1,521
-2,467
-62% -$519K 0.01% 1684
2022
Q4 		$948K Buy
3,988
+881
+28% +$188K 0.03% 715
2022
Q3 		$622K Sell
3,107
-8,183
-72% -$1.56M 0.02% 923
2022
Q2 		$1.65M Buy
11,290
+3,782
+50% +$537K 0.06% 357
2022
Q1 		$1.23M Buy
7,508
+5,383
+253% +$820K 0.04% 530
2021
Q4 		$360K Buy
+2,125
New +$395K 0.02% 707
2021
Q3 		– Sell
-2,066
Closed -$350K – 1519
2021
Q2 		$350K Buy
+2,066
New +$303K 0.01% 880
2020
Q1 		– Sell
-2,404
Closed -$277K – 1324
2019
Q4 		$277K Buy
+2,404
New +$240K ﹤0.01% 1849
2018
Q2 		– Sell
-2,524
Closed -$250K – 2615
2018
Q1 		$301K Buy
+2,524
New +$325K ﹤0.01% 2001
2017
Q4 		– Sell
-2,039
Closed -$256K – 1714
2017
Q3 		$240K Sell
2,039
-1,413
-41% -$121K 0.02% 483
2017
Q2 		$275K Buy
+3,452
New +$221K 0.05% 391

Other funds holding ALNY

Capital World Investors
Capital World Investors Los Angeles, California $733B AUM 35.63% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Capital Research Global Investors
Capital Research Global Investors Los Angeles, California $645B AUM 30.41% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Baillie Gifford & Co
Baillie Gifford & Co Edinburgh, United Kingdom $97.9B AUM 20.73% 1-Year Est. Return

Two Sigma Securities's ALNY Position: Q4 2025 in Review

Two Sigma Securities sold out of Alnylam Pharmaceuticals (ALNY) in Q4 2025, closing a stake of 1,740 shares — an estimated $793K sold.

Two Sigma Securities first reported a position in ALNY in Q2 2017 and held it in 16 quarters. The position peaked at $13.2M in Q2 2024. 848 funds tracked by Wall St. Rank hold ALNY as of Q4 2025.

  • Two Sigma Securities reported no remaining Alnylam Pharmaceuticals position as of Q4 2025 after selling out during the quarter.
  • Two Sigma Securities sold 1,740 Alnylam Pharmaceuticals shares in Q4 2025, an estimated $793K.
  • Two Sigma Securities first reported a position in Alnylam Pharmaceuticals in Q2 2017 and held it in 16 quarters.
  • Two Sigma Securities's Alnylam Pharmaceuticals position peaked at $13.2M in Q2 2024.
  • 848 funds tracked by Wall St. Rank held Alnylam Pharmaceuticals as of Q4 2025.

Based on Two Sigma Securities's 13F filing for Q4 2025, filed 17 Feb 2026.