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Alnylam Pharmaceuticals

785 hedge funds and large institutions have $42.5B invested in Alnylam Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 102 funds opening new positions, 320 increasing their positions, 257 reducing their positions, and 153 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

18% less capital invested

Capital invested by funds: $51.7B → $42.5B (-$9.26B)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

33% less first-time investments, than exits

New positions opened: 102 | Existing positions closed: 153

Holders
785
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$450M
Puts
$205M
Net Calls
Net Calls Change

Top Buyers

1 +$1.17B
2 +$916M
3 +$546M
4
Two Sigma Investments
Two Sigma Investments
New York
+$468M
5
ClearBridge Investments
ClearBridge Investments
New York
+$258M

Top Sellers

1 -$1.87B
2 -$450M
3 -$448M
4
Invesco
Invesco
Georgia
-$297M
5
1832 Asset Management
1832 Asset Management
Ontario, Canada
-$175M
Name Holding Trade Value Shares
Change
Change in
Stake
QIM
376
Quantitative Investment Management
Virginia
$1.28M
NYLIM
377
New York Life Investment Management
New York
$1.25M
DAM
378
Draper Asset Management
New York
$1.25M
ZBNA
379
Zions Bancorporation, National Association
Utah
$1.2M
CI Investments Inc
380
CI Investments Inc
Ontario, Canada
$1.19M
SC
381
SummitTX Capital
Texas
$1.19M
STA
382
Summit Trail Advisors
New York
$1.19M
LNWTC
383
Laird Norton Wetherby Trust Company
Washington
$1.16M
KCM
384
Kennedy Capital Management
Missouri
$1.16M
DZ Bank
385
DZ Bank
Germany
$1.16M
BC
386
Burney Company
Virginia
$1.13M
SPAS
387
Spectrum Planning & Advisory Services
California
$1.11M
LOAMS
388
Lombard Odier Asset Management (Switzerland)
Switzerland
$1.1M
KRSITF
389
Kentucky Retirement Systems Insurance Trust Fund
Kentucky
$1.09M
SLI
390
Sumitomo Life Insurance
Japan
$1.09M
ETC
391
Exchange Traded Concepts
Oklahoma
$1.08M
VFA
392
Values First Advisors
Tennessee
$1.07M
KeyBank National Association
393
KeyBank National Association
Ohio
$1.07M
P
394
&Partners
Tennessee
$1.07M
JSSH
395
J. Safra Sarasin Holding
$1.07M
GAM
396
Generali Asset Management
Italy
$1.06M
BM
397
Brandywine Managers
Delaware
$1.05M
SMH
398
Sanders Morris Harris
Texas
$1.04M
GD
399
Grandfield & Dodd
New York
$1.02M
CFO
400
Callan Family Office
Pennsylvania
$1M