|
1
|
Janus Henderson Group
London,
|
$207M
|
+$28.1M
|
+613,443
|
+16%
|
|
|
2
|
Alkeon Capital Management
New York
|
$162M
|
+$11.3M
|
+246,650
|
+8%
|
|
|
3
|
|
$155M
|
+$24.6M
|
+537,776
|
+19%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$154M
|
+$30.5M
|
+665,963
|
+25%
|
|
|
5
|
Adage Capital Partners
Boston,
Massachusetts
|
$142M
|
+$30.2M
|
+658,986
|
+28%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$125M
|
+$25.1M
|
+546,981
|
+26%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$121M
|
+$66.3M
|
+1,446,243
|
+127%
|
|
|
8
|
Baker Bros. Advisors
New York
|
$111M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$105M
|
+$432K
|
+9,424
|
+0.4%
|
|
|
10
|
Perceptive Advisors
New York
|
$90.6M
|
+$64.9M
|
+1,417,150
|
+271%
|
|
|
11
|
Redmile Group
San Francisco,
California
|
$84.6M
|
-$10.7M
|
-232,717
|
-11%
|
|
|
12
|
General Atlantic
New York
|
$83.4M
|
+$81.8M
|
+1,785,714
|
New
|
|
|
13
|
Boxer Capital
San Diego,
California
|
$78.3M
|
+$38.7M
|
+845,238
|
+102%
|
|
|
14
|
Commodore Capital
New York
|
$78.2M
|
+$40.6M
|
+885,000
|
+112%
|
|
|
15
|
Skorpios Trust
Limassol,
Cyprus
|
$75.7M
|
-$75.6M
|
-1,650,000
|
-50%
|
|
|
16
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$72.4M
|
+$4.42M
|
+96,500
|
+7%
|
|
|
17
|
Yiheng Capital Management
San Francisco,
California
|
$56.1M
|
+$3.47M
|
+75,800
|
+7%
|
|
|
18
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$53.4M
|
+$52.4M
|
+1,144,082
|
New
|
|
|
19
|
Avidity Partners Management
Dallas,
Texas
|
$47.9M
|
-$65.2M
|
-1,422,000
|
-58%
|
|
|
20
|
Marshall Wace
London,
United Kingdom
|
$43.1M
|
-$7.27M
|
-158,667
|
-15%
|
|
|
21
|
Wellington Management Group
Boston,
Massachusetts
|
$42.1M
|
-$11.9M
|
-259,337
|
-22%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$38.5M
|
+$7.28M
|
+158,780
|
+24%
|
|
|
23
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$27.7M
|
–
|
–
|
–
|
|
|
24
|
Logos Global Management
San Francisco,
California
|
$24.3M
|
+$5.5M
|
+120,000
|
+30%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$21.5M
|
+$4.7M
|
+102,662
|
+29%
|
|
