|
1
|
Avidity Partners Management
Dallas,
Texas
|
$210M
|
+$30.1M
|
+703,000
|
+23%
|
|
|
2
|
Janus Henderson Group
London,
|
$183M
|
-$40.1M
|
-935,285
|
-22%
|
|
|
3
|
Skorpios Trust
Limassol,
Cyprus
|
$179M
|
-$70.1M
|
-1,636,000
|
-33%
|
|
|
4
|
Alkeon Capital Management
New York
|
$178M
|
+$3.5M
|
+81,656
|
+3%
|
|
|
5
|
|
$151M
|
+$17.7M
|
+413,052
|
+18%
|
|
|
6
|
Redmile Group
San Francisco,
California
|
$144M
|
+$44.6M
|
+1,041,827
|
+65%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$137M
|
+$83.7M
|
+1,953,347
|
+357%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$132M
|
+$40.2M
|
+938,613
|
+64%
|
|
|
9
|
Baker Bros. Advisors
New York
|
$130M
|
–
|
–
|
–
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$116M
|
+$16.1M
|
+375,978
|
+22%
|
|
|
11
|
Marshall Wace
London,
United Kingdom
|
$82.4M
|
+$32.2M
|
+752,524
|
+100%
|
|
|
12
|
Yiheng Capital Management
San Francisco,
California
|
$80.5M
|
-$27M
|
-630,241
|
-30%
|
|
|
13
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$76.8M
|
+$1.31M
|
+30,681
|
+2%
|
|
|
14
|
Adage Capital Partners
Boston,
Massachusetts
|
$72.6M
|
+$19.4M
|
+452,477
|
+52%
|
|
|
15
|
RA Capital Management
Boston,
Massachusetts
|
$52.6M
|
–
|
–
|
–
|
|
|
16
|
Wellington Management Group
Boston,
Massachusetts
|
$48M
|
+$3.41M
|
+79,600
|
+10%
|
|
|
17
|
Boxer Capital
San Diego,
California
|
$45.6M
|
–
|
–
|
–
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$34.7M
|
+$4.72M
|
+110,091
|
+21%
|
|
|
19
|
Paradigm Biocapital Advisors
New York
|
$33.1M
|
-$9.8M
|
-228,721
|
-27%
|
|
|
20
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$32.6M
|
-$17.1M
|
-400,000
|
-40%
|
|
|
21
|
Commodore Capital
New York
|
$29.4M
|
-$8.84M
|
-206,396
|
-28%
|
|
|
22
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$23.4M
|
+$17.8M
|
+414,957
|
+3,261%
|
|
|
23
|
Logos Global Management
San Francisco,
California
|
$21.9M
|
–
|
–
|
–
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$19.7M
|
+$4.1M
|
+95,767
|
+36%
|
|
|
25
|
Perceptive Advisors
New York
|
$19.2M
|
-$3.41M
|
-79,475
|
-18%
|
|