|
1
|
Janus Henderson Group
London,
|
$146M
|
+$21M
|
+471,502
|
+14%
|
|
|
2
|
Skorpios Trust
Limassol,
Cyprus
|
$125M
|
–
|
–
|
–
|
|
|
3
|
Alkeon Capital Management
New York
|
$123M
|
-$1.03M
|
-23,185
|
-0.7%
|
|
|
4
|
|
$106M
|
+$1.11M
|
+24,848
|
+0.9%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$100M
|
+$9.93M
|
+222,643
|
+9%
|
|
|
6
|
Avidity Partners Management
Dallas,
Texas
|
$93.6M
|
-$61.4M
|
-1,378,000
|
-36%
|
|
|
7
|
Adage Capital Partners
Boston,
Massachusetts
|
$91.4M
|
+$47.5M
|
+1,064,914
|
+80%
|
|
|
8
|
Baker Bros. Advisors
New York
|
$90.6M
|
–
|
–
|
–
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$85.4M
|
-$12M
|
-270,162
|
-11%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$81.8M
|
+$995K
|
+22,322
|
+1%
|
|
|
11
|
Redmile Group
San Francisco,
California
|
$78.2M
|
-$26.2M
|
-588,523
|
-22%
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$55.6M
|
+$2.39M
|
+53,600
|
+4%
|
|
|
13
|
Wellington Management Group
Boston,
Massachusetts
|
$44.4M
|
+$12.7M
|
+284,443
|
+32%
|
|
|
14
|
Fidelity Investments
Boston,
Massachusetts
|
$43.7M
|
+$50M
|
+1,120,874
|
+5,492%
|
|
|
15
|
Yiheng Capital Management
San Francisco,
California
|
$43.1M
|
-$15.3M
|
-343,114
|
-23%
|
|
|
16
|
Marshall Wace
London,
United Kingdom
|
$41.4M
|
-$18.8M
|
-421,639
|
-28%
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$32.7M
|
+$26.5M
|
+593,991
|
+227%
|
|
|
18
|
Boxer Capital
San Diego,
California
|
$31.8M
|
–
|
–
|
–
|
|
|
19
|
Commodore Capital
New York
|
$30.2M
|
+$11.3M
|
+252,924
|
+47%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$25.5M
|
+$1.45M
|
+32,547
|
+5%
|
|
|
21
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$22.7M
|
–
|
–
|
–
|
|
|
22
|
Perceptive Advisors
New York
|
$20M
|
+$7.71M
|
+173,000
|
+49%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$19.9M
|
+$4.1M
|
+91,892
|
+21%
|
|
|
24
|
Logos Global Management
San Francisco,
California
|
$15.3M
|
–
|
–
|
–
|
|
|
25
|
Eventide Asset Management
Boston,
Massachusetts
|
$14.5M
|
+$16.9M
|
+379,120
|
New
|
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