|
1
|
Skorpios Trust
Limassol,
Cyprus
|
$167M
|
–
|
–
|
–
|
|
|
2
|
Janus Henderson Group
London,
|
$146M
|
+$18.5M
|
+1,207,147
|
+39%
|
|
|
3
|
Alkeon Capital Management
New York
|
$108M
|
+$8.3M
|
+542,588
|
+21%
|
|
|
4
|
Avidity Partners Management
Dallas,
Texas
|
$106M
|
+$47.8M
|
+3,122,000
|
New
|
|
|
5
|
Baker Bros. Advisors
New York
|
$80.6M
|
+$34.4M
|
+2,250,000
|
+1,901%
|
|
|
6
|
|
$79.9M
|
+$3.89M
|
+254,236
|
+12%
|
|
|
7
|
|
$72.1M
|
+$3.9M
|
+255,193
|
+14%
|
|
|
8
|
Yiheng Capital Management
San Francisco,
California
|
$71.5M
|
+$3.31M
|
+216,448
|
+11%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$59.3M
|
+$6.57M
|
+429,579
|
+33%
|
|
|
10
|
Redmile Group
San Francisco,
California
|
$54.2M
|
+$58.1K
|
+3,800
|
+0.2%
|
|
|
11
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$49.8M
|
+$15.4M
|
+1,007,122
|
+221%
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$46.6M
|
+$10.6M
|
+690,459
|
+102%
|
|
|
13
|
Atlas Venture Life Science Advisors
Cambridge,
Massachusetts
|
$33.9M
|
-$18.9M
|
-1,238,000
|
-55%
|
|
|
14
|
RA Capital Management
Boston,
Massachusetts
|
$32.7M
|
+$14.7M
|
+958,980
|
New
|
|
|
15
|
Adage Capital Partners
Boston,
Massachusetts
|
$29.7M
|
+$13.3M
|
+872,500
|
New
|
|
|
16
|
Paradigm Biocapital Advisors
New York
|
$28.4M
|
+$12.7M
|
+833,265
|
New
|
|
|
17
|
Boxer Capital
San Diego,
California
|
$28.3M
|
–
|
–
|
–
|
|
|
18
|
Wellington Management Group
Boston,
Massachusetts
|
$27.1M
|
+$1.44M
|
+94,019
|
+13%
|
|
|
19
|
Deep Track Capital
Greenwich,
Connecticut
|
$26.9M
|
+$12.1M
|
+790,926
|
New
|
|
|
20
|
Marshall Wace
London,
United Kingdom
|
$25.6M
|
-$3.9M
|
-254,842
|
-25%
|
|
|
21
|
Commodore Capital
New York
|
$25.3M
|
+$11.4M
|
+743,472
|
New
|
|
|
22
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$23.2M
|
-$10.4M
|
-679,052
|
-50%
|
|
|
23
|
venBio Partners
San Francisco,
California
|
$20.3M
|
-$24.1M
|
-1,575,181
|
-73%
|
|
|
24
|
State Street
Boston,
Massachusetts
|
$18.6M
|
+$838K
|
+54,770
|
+11%
|
|
|
25
|
Geode Capital Management
Boston,
Massachusetts
|
$17.8M
|
+$846K
|
+55,304
|
+12%
|
|
