|
1
|
Baker Bros. Advisors
New York
|
–
|
-US$ 1,14 bi
|
-11.660.432
|
Encerrada
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-US$ 541 mi
|
-5.543.741
|
Encerrada
|
|
|
3
|
Capital Research Global Investors
Los Angeles,
California
|
–
|
-US$ 442 mi
|
-4.527.358
|
Encerrada
|
|
|
4
|
Columbia Wanger Asset Management
Chicago,
Illinois
|
–
|
-US$ 317 mi
|
-3.245.542
|
Encerrada
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-US$ 152 mi
|
-1.554.979
|
Encerrada
|
|
|
6
|
Capital World Investors
Los Angeles,
California
|
–
|
-US$ 123 mi
|
-1.262.798
|
Encerrada
|
|
|
7
|
BlackRock Fund Advisors
San Francisco,
California
|
–
|
-US$ 103 mi
|
-1.058.768
|
Encerrada
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
–
|
-US$ 101 mi
|
-1.037.935
|
Encerrada
|
|
|
9
|
BB Biotech
Schaffhausen,
Switzerland
|
–
|
-US$ 100 mi
|
-1.025.476
|
Encerrada
|
|
|
10
|
Wells Fargo
San Francisco,
California
|
–
|
-US$ 77,8 mi
|
-797.807
|
Encerrada
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
–
|
-US$ 59,6 mi
|
-610.716
|
Encerrada
|
|
|
12
|
Wellington Management Group
Boston,
Massachusetts
|
–
|
-US$ 57,9 mi
|
-593.823
|
Encerrada
|
|
|
13
|
State Street
Boston,
Massachusetts
|
–
|
-US$ 56,9 mi
|
-583.000
|
Encerrada
|
|
|
14
|
Janus Henderson Investors US
Denver,
Colorado
|
–
|
-US$ 55,8 mi
|
-572.037
|
Encerrada
|
|
|
15
|
AllianceBernstein
Nashville,
Tennessee
|
–
|
-US$ 48 mi
|
-492.190
|
Encerrada
|
|
|
16
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
–
|
-US$ 37,9 mi
|
-388.980
|
Encerrada
|
|
|
17
|
Eagle Asset Management
St Petersburg,
Florida
|
–
|
-US$ 36,3 mi
|
-371.816
|
Encerrada
|
|
|
18
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
–
|
-US$ 35,7 mi
|
-365.684
|
Encerrada
|
|
|
19
|
|
–
|
-US$ 35,5 mi
|
-364.160
|
Encerrada
|
|
|
20
|
|
–
|
-US$ 27,9 mi
|
-286.447
|
Encerrada
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
–
|
-US$ 26 mi
|
-266.963
|
Encerrada
|
|
|
22
|
|
–
|
-US$ 19,7 mi
|
-201.582
|
Encerrada
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
–
|
-US$ 19,4 mi
|
-198.689
|
Encerrada
|
|
|
24
|
BlackRock Advisors
Wilmington,
Delaware
|
–
|
-US$ 18,2 mi
|
-187.036
|
Encerrada
|
|
|
25
|
|
–
|
-US$ 17,2 mi
|
-176.224
|
Encerrada
|
|
