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EDIT

Nome Posição Valor negociado Ações
Variação 		Variação na
participação
Fidelity Investments
1
Fidelity Investments
Massachusetts
US$ 133 mi +US$ 1,69 mi +50.031 +0,9%
Flagship Ventures Fund IV General Partner
2
Flagship Ventures Fund IV General Partner
Massachusetts
US$ 121 mi +US$ 167 mi +4.955.316 Nova
Polaris Venture Management Co VI
3
Polaris Venture Management Co VI
Massachusetts
US$ 114 mi – – –
Viking Global Investors
4
Viking Global Investors
Connecticut
US$ 41,7 mi -US$ 14,4 mi -426.122 -20%
Deerfield Management
5
Deerfield Management
New York
US$ 41,7 mi – – –
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
US$ 33,5 mi +US$ 142 mil +4.220 +0,3%
Vanguard Group
7
Vanguard Group
Pennsylvania
US$ 13 mi -US$ 7,33 mi -217.323 -29%
Morgan Stanley
8
Morgan Stanley
New York
US$ 7,28 mi +US$ 5,25 mi +155.706 +109%
Capital World Investors
9
Capital World Investors
California
US$ 7,2 mi – – –
Alphabet Inc
10
Alphabet Inc
California
US$ 6,26 mi – – –
Jennison Associates
11
Jennison Associates
New York
US$ 4,13 mi – – –
BlackRock Fund Advisors
12
BlackRock Fund Advisors
California
US$ 3,99 mi +US$ 151 mil +4.466 +3%
Omega Fund Management
13
Omega Fund Management
Massachusetts
US$ 2,56 mi +US$ 34 +1 +0%
State Street
14
State Street
Massachusetts
US$ 2,45 mi +US$ 2,22 mi +65.723 +190%
EcoR1 Capital
15
EcoR1 Capital
California
US$ 2,08 mi -US$ 82,7 mil -2.452 -3%
Northern Trust
16
Northern Trust
Illinois
US$ 1,78 mi +US$ 1,96 mi +58.024 +387%
BlackRock Institutional Trust
17
BlackRock Institutional Trust
California
US$ 1,61 mi +US$ 279 mil +8.265 +14%
Wildcat Capital Management
18
Wildcat Capital Management
New York
US$ 1,46 mi -US$ 6,34 mi -187.968 -76%
Geode Capital Management
19
Geode Capital Management
Massachusetts
US$ 1,38 mi -US$ 1,35 mil -40 -0,1%
Goldman Sachs
20
Goldman Sachs
New York
US$ 1,24 mi -US$ 641 mil -19.000 -27%
Bank of New York Mellon
21
Bank of New York Mellon
New York
US$ 677 mil +US$ 355 mil +10.514 +61%
BlackRock Investment Management
22
BlackRock Investment Management
Delaware
US$ 646 mil +US$ 36,4 mil +1.079 +4%
Renaissance Technologies
23
Renaissance Technologies
New York
US$ 544 mil +US$ 752 mil +22.304 Nova
TIAA CREF Investment Management
24
TIAA CREF Investment Management
New York
US$ 494 mil +US$ 177 mil +5.254 +35%
Charles Schwab
25
Charles Schwab
California
US$ 473 mil +US$ 357 mil +10.594 +121%
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