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EDIT

Nombre Posición Valor operado Cambio en
acciones 		Cambio en la
participación
Fidelity Investments
1
Fidelity Investments
Massachusetts
USD 133 M +USD 1.69 M +50,031 +0.9%
Flagship Ventures Fund IV General Partner
2
Flagship Ventures Fund IV General Partner
Massachusetts
USD 121 M +USD 167 M +4,955,316 Nuevas
Polaris Venture Management Co VI
3
Polaris Venture Management Co VI
Massachusetts
USD 114 M – – –
Viking Global Investors
4
Viking Global Investors
Connecticut
USD 41.7 M -USD 14.4 M -426,122 -20%
Deerfield Management
5
Deerfield Management
New York
USD 41.7 M – – –
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
USD 33.5 M +USD 142 k +4,220 +0.3%
Vanguard Group
7
Vanguard Group
Pennsylvania
USD 13 M -USD 7.33 M -217,323 -29%
Morgan Stanley
8
Morgan Stanley
New York
USD 7.28 M +USD 5.25 M +155,706 +109%
Capital World Investors
9
Capital World Investors
California
USD 7.2 M – – –
Alphabet Inc
10
Alphabet Inc
California
USD 6.26 M – – –
Jennison Associates
11
Jennison Associates
New York
USD 4.13 M – – –
BlackRock Fund Advisors
12
BlackRock Fund Advisors
California
USD 3.99 M +USD 151 k +4,466 +3%
Omega Fund Management
13
Omega Fund Management
Massachusetts
USD 2.56 M +USD 34 +1 +0%
State Street
14
State Street
Massachusetts
USD 2.45 M +USD 2.22 M +65,723 +190%
EcoR1 Capital
15
EcoR1 Capital
California
USD 2.08 M -USD 82.7 k -2,452 -3%
Northern Trust
16
Northern Trust
Illinois
USD 1.78 M +USD 1.96 M +58,024 +387%
BlackRock Institutional Trust
17
BlackRock Institutional Trust
California
USD 1.61 M +USD 279 k +8,265 +14%
Wildcat Capital Management
18
Wildcat Capital Management
New York
USD 1.46 M -USD 6.34 M -187,968 -76%
Geode Capital Management
19
Geode Capital Management
Massachusetts
USD 1.38 M -USD 1.35 k -40 -0.1%
Goldman Sachs
20
Goldman Sachs
New York
USD 1.24 M -USD 641 k -19,000 -27%
Bank of New York Mellon
21
Bank of New York Mellon
New York
USD 677 k +USD 355 k +10,514 +61%
BlackRock Investment Management
22
BlackRock Investment Management
Delaware
USD 646 k +USD 36.4 k +1,079 +4%
Renaissance Technologies
23
Renaissance Technologies
New York
USD 544 k +USD 752 k +22,304 Nuevas
TIAA CREF Investment Management
24
TIAA CREF Investment Management
New York
USD 494 k +USD 177 k +5,254 +35%
Charles Schwab
25
Charles Schwab
California
USD 473 k +USD 357 k +10,594 +121%
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