|
1
|
Decheng Capital
Menlo Park,
California
|
–
|
-US$ 330 mi
|
-8.317.924
|
Encerrada
|
|
|
2
|
Avoro Capital Advisors
New York
|
–
|
-US$ 229 mi
|
-5.775.000
|
Encerrada
|
|
|
3
|
|
–
|
-US$ 142 mi
|
-3.575.092
|
Encerrada
|
|
|
4
|
Frazier Life Sciences Management
Palo Alto,
California
|
–
|
-US$ 124 mi
|
-3.131.008
|
Encerrada
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
–
|
-US$ 122 mi
|
-3.080.220
|
Encerrada
|
|
|
6
|
State Street
Boston,
Massachusetts
|
–
|
-US$ 113 mi
|
-2.845.839
|
Encerrada
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-US$ 108 mi
|
-2.712.285
|
Encerrada
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
–
|
-US$ 107 mi
|
-2.700.000
|
Encerrada
|
|
|
9
|
|
–
|
-US$ 106 mi
|
-2.680.496
|
Encerrada
|
|
|
10
|
Lynx1 Capital Management
San Juan,
Puerto Rico
|
–
|
-US$ 89,3 mi
|
-2.253.183
|
Encerrada
|
|
|
11
|
Paradigm Biocapital Advisors
New York
|
–
|
-US$ 84,1 mi
|
-2.121.163
|
Encerrada
|
|
|
12
|
Darwin Global Management
St. Helier,
Jersey
|
–
|
-US$ 78,6 mi
|
-1.982.016
|
Encerrada
|
|
|
13
|
Commodore Capital
New York
|
–
|
-US$ 54,5 mi
|
-1.375.000
|
Encerrada
|
|
|
14
|
Octagon Capital Advisors
New York
|
–
|
-US$ 49,2 mi
|
-1.241.300
|
Encerrada
|
|
|
15
|
Avidity Partners Management
Dallas,
Texas
|
–
|
-US$ 46,6 mi
|
-1.174.700
|
Encerrada
|
|
|
16
|
Great Point Partners
Greenwich,
Connecticut
|
–
|
-US$ 44,7 mi
|
-1.128.499
|
Encerrada
|
|
|
17
|
Franklin Resources
San Mateo,
California
|
–
|
-US$ 43,3 mi
|
-1.093.203
|
Encerrada
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-US$ 36,1 mi
|
-910.599
|
Encerrada
|
|
|
19
|
|
–
|
-US$ 31,3 mi
|
-789.645
|
Encerrada
|
|
|
20
|
Two Sigma Advisers
New York
|
–
|
-US$ 26,5 mi
|
-668.775
|
Encerrada
|
|
|
21
|
Vivo Capital
Palo Alto,
California
|
–
|
-US$ 20,8 mi
|
-520.505
|
Encerrada
|
|
|
22
|
Two Sigma Investments
New York
|
–
|
-US$ 20,6 mi
|
-519.971
|
Encerrada
|
|
|
23
|
Nuveen
Charlotte,
North Carolina
|
–
|
-US$ 20,3 mi
|
-513.175
|
Encerrada
|
|
|
24
|
First Light Asset Management
Edina,
Minnesota
|
–
|
-US$ 19,9 mi
|
-501.243
|
Encerrada
|
|
|
25
|
Janus Henderson Group
London,
|
–
|
-US$ 17,8 mi
|
-450.827
|
Encerrada
|
|
