|
1
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-US$ 31 mi
|
-4.582.532
|
Encerrada
|
|
|
2
|
NEA Management Company
Timonium,
Maryland
|
–
|
-US$ 29,1 mi
|
-4.298.488
|
Encerrada
|
|
|
3
|
5AM Venture Management
San Francisco,
California
|
–
|
-US$ 28 mi
|
-4.135.784
|
Encerrada
|
|
|
4
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
–
|
-US$ 27 mi
|
-3.988.967
|
Encerrada
|
|
|
5
|
|
–
|
-US$ 18,9 mi
|
-2.800.566
|
Encerrada
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
–
|
-US$ 13,4 mi
|
-1.975.984
|
Encerrada
|
|
|
7
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
–
|
-US$ 12,1 mi
|
-1.794.088
|
Encerrada
|
|
|
8
|
Sofinnova Investments
Menlo Park,
California
|
–
|
-US$ 10,2 mi
|
-1.515.074
|
Encerrada
|
|
|
9
|
TCG Crossover Management
Palo Alto,
California
|
–
|
-US$ 9,13 mi
|
-1.350.006
|
Encerrada
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
–
|
-US$ 9,1 mi
|
-1.346.141
|
Encerrada
|
|
|
11
|
|
–
|
-US$ 8,71 mi
|
-1.288.358
|
Encerrada
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-US$ 6,16 mi
|
-910.851
|
Encerrada
|
|
|
13
|
Marshall Wace
London,
United Kingdom
|
–
|
-US$ 5,55 mi
|
-820.934
|
Encerrada
|
|
|
14
|
|
–
|
-US$ 5,25 mi
|
-776.992
|
Encerrada
|
|
|
15
|
Kynam Capital Management
Princeton,
New Jersey
|
–
|
-US$ 4,86 mi
|
-718.394
|
Encerrada
|
|
|
16
|
Millennium Management
New York
|
–
|
-US$ 4,67 mi
|
-690.452
|
Encerrada
|
|
|
17
|
Laurion Capital Management
New York
|
–
|
-US$ 3,08 mi
|
-456.000
|
Encerrada
|
|
|
18
|
Cormorant Asset Management
Boston,
Massachusetts
|
–
|
-US$ 2,67 mi
|
-394.500
|
Encerrada
|
|
|
19
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
–
|
-US$ 1,43 mi
|
-212.036
|
Encerrada
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-US$ 1,31 mi
|
-193.842
|
Encerrada
|
|
|
21
|
|
–
|
-US$ 1,11 mi
|
-164.649
|
Encerrada
|
|
|
22
|
Oasis Management Company
Grand Cayman,
Cayman Islands
|
–
|
-US$ 791 mil
|
-117.000
|
Encerrada
|
|
|
23
|
Point72 Asset Management
Stamford,
Connecticut
|
–
|
-US$ 748 mil
|
-110.679
|
Encerrada
|
|
|
24
|
Bollard Group
Boston,
Massachusetts
|
–
|
-US$ 676 mil
|
-99.998
|
Encerrada
|
|
|
25
|
Renaissance Technologies
New York
|
–
|
-US$ 668 mil
|
-98.800
|
Encerrada
|
|
