|
1
|
Fidelity Investments
Boston,
Massachusetts
|
–
|
-$31M
|
-4,582,532
|
Closed
|
|
|
2
|
NEA Management Company
Timonium,
Maryland
|
–
|
-$29.1M
|
-4,298,488
|
Closed
|
|
|
3
|
5AM Venture Management
San Francisco,
California
|
–
|
-$28M
|
-4,135,784
|
Closed
|
|
|
4
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
–
|
-$27M
|
-3,988,967
|
Closed
|
|
|
5
|
|
–
|
-$18.9M
|
-2,800,566
|
Closed
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
–
|
-$13.4M
|
-1,975,984
|
Closed
|
|
|
7
|
Pivotal bioVenture Partners Investment Advisor
San Francisco,
California
|
–
|
-$12.1M
|
-1,794,088
|
Closed
|
|
|
8
|
Sofinnova Investments
Menlo Park,
California
|
–
|
-$10.2M
|
-1,515,074
|
Closed
|
|
|
9
|
TCG Crossover Management
Palo Alto,
California
|
–
|
-$9.13M
|
-1,350,006
|
Closed
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
–
|
-$9.1M
|
-1,346,141
|
Closed
|
|
|
11
|
|
–
|
-$8.71M
|
-1,288,358
|
Closed
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$6.16M
|
-910,851
|
Closed
|
|
|
13
|
Marshall Wace
London,
United Kingdom
|
–
|
-$5.55M
|
-820,934
|
Closed
|
|
|
14
|
|
–
|
-$5.25M
|
-776,992
|
Closed
|
|
|
15
|
Kynam Capital Management
Princeton,
New Jersey
|
–
|
-$4.86M
|
-718,394
|
Closed
|
|
|
16
|
Millennium Management
New York
|
–
|
-$4.67M
|
-690,452
|
Closed
|
|
|
17
|
Laurion Capital Management
New York
|
–
|
-$3.08M
|
-456,000
|
Closed
|
|
|
18
|
Cormorant Asset Management
Boston,
Massachusetts
|
–
|
-$2.67M
|
-394,500
|
Closed
|
|
|
19
|
Ensign Peak Advisors
Salt Lake City,
Utah
|
–
|
-$1.43M
|
-212,036
|
Closed
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$1.31M
|
-193,842
|
Closed
|
|
|
21
|
|
–
|
-$1.11M
|
-164,649
|
Closed
|
|
|
22
|
Oasis Management Company
Grand Cayman,
Cayman Islands
|
–
|
-$791K
|
-117,000
|
Closed
|
|
|
23
|
Point72 Asset Management
Stamford,
Connecticut
|
–
|
-$748K
|
-110,679
|
Closed
|
|
|
24
|
Bollard Group
Boston,
Massachusetts
|
–
|
-$676K
|
-99,998
|
Closed
|
|
|
25
|
Renaissance Technologies
New York
|
–
|
-$668K
|
-98,800
|
Closed
|
|