|
1
|
BML Capital Management
Zionsville,
Indiana
|
–
|
-US$ 13,9 mi
|
-3.057.526
|
Encerrada
|
|
|
2
|
Principia Wealth Advisory
Dallas,
Texas
|
–
|
-US$ 9,41 mi
|
-2.077.946
|
Encerrada
|
|
|
3
|
Frazier Life Sciences Management
Palo Alto,
California
|
–
|
-US$ 9,41 mi
|
-2.077.431
|
Encerrada
|
|
|
4
|
TCG Crossover Management
Palo Alto,
California
|
–
|
-US$ 7,56 mi
|
-1.668.174
|
Encerrada
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-US$ 3,95 mi
|
-872.041
|
Encerrada
|
|
|
6
|
5AM Venture Management
San Francisco,
California
|
–
|
-US$ 2,45 mi
|
-541.666
|
Encerrada
|
|
|
7
|
Versant Venture Management
San Francisco,
California
|
–
|
-US$ 2,3 mi
|
-506.821
|
Encerrada
|
|
|
8
|
|
–
|
-US$ 1,82 mi
|
-402.581
|
Encerrada
|
|
|
9
|
Renaissance Technologies
New York
|
–
|
-US$ 1,65 mi
|
-363.496
|
Encerrada
|
|
|
10
|
Pale Fire Capital SE
Prague,
Czech Republic
|
–
|
-US$ 1,65 mi
|
-363.282
|
Encerrada
|
|
|
11
|
Millennium Management
New York
|
–
|
-US$ 1,47 mi
|
-324.422
|
Encerrada
|
|
|
12
|
|
–
|
-US$ 1,41 mi
|
-311.394
|
Encerrada
|
|
|
13
|
Soleus Capital Management
Greenwich,
Connecticut
|
–
|
-US$ 1,3 mi
|
-287.246
|
Encerrada
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
–
|
-US$ 1,06 mi
|
-234.541
|
Encerrada
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-US$ 837 mil
|
-184.762
|
Encerrada
|
|
|
16
|
Regeneron Pharmaceuticals
Tarrytown,
New York
|
–
|
-US$ 820 mil
|
-180.909
|
Encerrada
|
|
|
17
|
Waverly Advisors
Birmingham,
Alabama
|
–
|
-US$ 729 mil
|
-160.991
|
Encerrada
|
|
|
18
|
Two Sigma Investments
New York
|
–
|
-US$ 402 mil
|
-88.670
|
Encerrada
|
|
|
19
|
State Street
Boston,
Massachusetts
|
–
|
-US$ 311 mil
|
-68.734
|
Encerrada
|
|
|
20
|
Quinn Opportunity Partners
Charlottesville,
Virginia
|
–
|
-US$ 188 mil
|
-41.418
|
Encerrada
|
|
|
21
|
Two Sigma Advisers
New York
|
–
|
-US$ 172 mil
|
-38.071
|
Encerrada
|
|
|
22
|
Marshall Wace
London,
United Kingdom
|
–
|
-US$ 129 mil
|
-28.367
|
Encerrada
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
–
|
-US$ 127 mil
|
-28.058
|
Encerrada
|
|
|
24
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
–
|
-US$ 119 mil
|
-26.255
|
Encerrada
|
|
|
25
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
–
|
-US$ 98,4 mil
|
-21.730
|
Encerrada
|
|
