|
1
|
BML Capital Management
Zionsville,
Indiana
|
–
|
-$13.9M
|
-3,057,526
|
Closed
|
|
|
2
|
Principia Wealth Advisory
Dallas,
Texas
|
–
|
-$9.41M
|
-2,077,946
|
Closed
|
|
|
3
|
Frazier Life Sciences Management
Palo Alto,
California
|
–
|
-$9.41M
|
-2,077,431
|
Closed
|
|
|
4
|
TCG Crossover Management
Palo Alto,
California
|
–
|
-$7.56M
|
-1,668,174
|
Closed
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
–
|
-$3.95M
|
-872,041
|
Closed
|
|
|
6
|
5AM Venture Management
San Francisco,
California
|
–
|
-$2.45M
|
-541,666
|
Closed
|
|
|
7
|
Versant Venture Management
San Francisco,
California
|
–
|
-$2.3M
|
-506,821
|
Closed
|
|
|
8
|
|
–
|
-$1.82M
|
-402,581
|
Closed
|
|
|
9
|
Renaissance Technologies
New York
|
–
|
-$1.65M
|
-363,496
|
Closed
|
|
|
10
|
Pale Fire Capital SE
Prague,
Czech Republic
|
–
|
-$1.65M
|
-363,282
|
Closed
|
|
|
11
|
Millennium Management
New York
|
–
|
-$1.47M
|
-324,422
|
Closed
|
|
|
12
|
|
–
|
-$1.41M
|
-311,394
|
Closed
|
|
|
13
|
Soleus Capital Management
Greenwich,
Connecticut
|
–
|
-$1.3M
|
-287,246
|
Closed
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
–
|
-$1.06M
|
-234,541
|
Closed
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
–
|
-$837K
|
-184,762
|
Closed
|
|
|
16
|
Regeneron Pharmaceuticals
Tarrytown,
New York
|
–
|
-$820K
|
-180,909
|
Closed
|
|
|
17
|
Waverly Advisors
Birmingham,
Alabama
|
–
|
-$729K
|
-160,991
|
Closed
|
|
|
18
|
Two Sigma Investments
New York
|
–
|
-$402K
|
-88,670
|
Closed
|
|
|
19
|
State Street
Boston,
Massachusetts
|
–
|
-$311K
|
-68,734
|
Closed
|
|
|
20
|
Quinn Opportunity Partners
Charlottesville,
Virginia
|
–
|
-$188K
|
-41,418
|
Closed
|
|
|
21
|
Two Sigma Advisers
New York
|
–
|
-$172K
|
-38,071
|
Closed
|
|
|
22
|
Marshall Wace
London,
United Kingdom
|
–
|
-$129K
|
-28,367
|
Closed
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
–
|
-$127K
|
-28,058
|
Closed
|
|
|
24
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
–
|
-$119K
|
-26,255
|
Closed
|
|
|
25
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
–
|
-$98.4K
|
-21,730
|
Closed
|
|
