Vanguard Group
DFTX

Vanguard Group’s Definium Therapeutics DFTX Stock Holding History

Vanguard Group’s Portfolio DFTX Stock Details DFTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$34.7M Buy
2,591,901
+579,027
+29% +$7.17M ﹤0.01% 2361
2025
Q3 		$23.7M Buy
2,012,874
+198,878
+11% +$1.85M ﹤0.01% 2543
2025
Q2 		$11.8M Buy
1,813,996
+47,449
+3% +$312K ﹤0.01% 2811
2025
Q1 		$10.3M Sell
1,766,547
-144,278
-8% -$1.03M ﹤0.01% 2830
2024
Q4 		$13.3M Sell
1,910,825
-37,482
-2% -$258K ﹤0.01% 2799
2024
Q3 		$11.1M Buy
1,948,307
+206,904
+12% +$1.44M ﹤0.01% 2907
2024
Q2 		$12.6M Buy
1,741,403
+1,178,482
+209% +$10.3M ﹤0.01% 2791
2024
Q1 		$5.29M Sell
562,921
-4,964
-0.9% -$28.3K ﹤0.01% 3281
2023
Q4 		$2.08M Hold
567,885
– – ﹤0.01% 3588
2023
Q3 		$1.78M Hold
567,885
– – ﹤0.01% 3630
2023
Q2 		$2.03M Sell
567,885
-6,054
-1% -$20.9K ﹤0.01% 3652
2023
Q1 		$1.82M Sell
573,939
-20,455
-3% -$68K ﹤0.01% 3713
2022
Q4 		$1.31M Buy
594,394
+581,486
+4,505% +$1.61M ﹤0.01% 3817
2022
Q3 		$45K Sell
12,908
-2,442
-16% -$23.4K ﹤0.01% 4552
2022
Q2 		$147K Sell
15,350
-111,527
-88% -$1.41M ﹤0.01% 4503
2022
Q1 		$2.11M Sell
126,877
-4,790
-4% -$83.1K ﹤0.01% 3934
2021
Q4 		$2.73M Buy
131,667
+6,640
+5% +$212K ﹤0.01% 3920
2021
Q3 		$4.37M Buy
125,027
+13,823
+12% +$598K ﹤0.01% 3747
2021
Q2 		$5.75M Buy
+111,204
New +$5.84M ﹤0.01% 3521

Other funds holding DFTX

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
TECP
Trails Edge Capital Partners Atlanta, Georgia $437M AUM
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
OCA
Octagon Capital Advisors New York $904M AUM 737.04% 1-Year Est. Return
Blackstone Inc
Blackstone Inc New York $25.6B AUM 26.83% 1-Year Est. Return

Vanguard Group's DFTX Position: Q4 2025 in Review

Vanguard Group increased its Definium Therapeutics (DFTX) stake by 29% in Q4 2025, buying an estimated $7.17M and bringing the position to 2,591,901 shares worth $34.7M. The position accounts for ﹤0.01% of the portfolio, ranked #2361.

Vanguard Group first reported a position in DFTX in Q2 2021 and has held it in 19 quarters since. 208 funds tracked by Wall St. Rank hold DFTX as of Q4 2025.

  • Vanguard Group held 2,591,901 shares of Definium Therapeutics worth $34.7M as of Q4 2025.
  • Vanguard Group bought 579,027 Definium Therapeutics shares in Q4 2025, an estimated $7.17M.
  • Definium Therapeutics made up ﹤0.01% of Vanguard Group's portfolio in Q4 2025, its #2361 holding.
  • Vanguard Group first reported a position in Definium Therapeutics in Q2 2021 and has held it in 19 quarters since.
  • 208 funds tracked by Wall St. Rank held Definium Therapeutics as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.