Two Sigma Investments’s Intuitive Surgical ISRG Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$648M Buy
1,405,334
+945,455
+206% +$478M 0.52% 22
2025
Q4
$260M Sell
459,879
-91,138
-17% -$48.5M 0.37% 17
2025
Q3
$246M Buy
551,017
+150,146
+37% +$72.1M 0.37% 32
2025
Q2
$218M Sell
400,871
-10,790
-3% -$5.64M 0.39% 47
2025
Q1
$204M Buy
411,661
+343,351
+503% +$190M 0.44% 41
2024
Q4
$35.7M Buy
68,310
+67,678
+10,709% +$35.3M 0.08% 319
2024
Q3
$310K Sell
632
-1,368
-68% -$637K ﹤0.01% 2655
2024
Q2
$890K Sell
2,000
-3
-0.1% -$1.2K ﹤0.01% 2054
2024
Q1
$799K Sell
2,003
-150,408
-99% -$56.8M ﹤0.01% 2093
2023
Q4
$51.4M Sell
152,411
-473,183
-76% -$141M 0.12% 218
2023
Q3
$183M Buy
625,594
+567,653
+980% +$177M 0.49% 35
2023
Q2
$19.8M Sell
57,941
-134,993
-70% -$40.8M 0.05% 413
2023
Q1
$49.3M Buy
192,934
+162,599
+536% +$40.1M 0.14% 172
2022
Q4
$8.05M Sell
30,335
-747,825
-96% -$182M 0.03% 640
2022
Q3
$146M Sell
778,160
-113,239
-13% -$24.3M 0.5% 44
2022
Q2
$179M Buy
891,399
+834,981
+1,480% +$196M 0.59% 32
2022
Q1
$17M Sell
56,418
-251,519
-82% -$73.5M 0.05% 425
2021
Q4
$111M Sell
307,937
-120,331
-28% -$41.4M 0.24% 100
2021
Q3
$142M Sell
428,268
-21,579
-5% -$7.25M 0.32% 73
2021
Q2
$138M Sell
449,847
-23,223
-5% -$6.52M 0.31% 59
2021
Q1
$117M Buy
473,070
+424,068
+865% +$107M 0.3% 64
2020
Q4
$13.4M Sell
49,002
-71,148
-59% -$17.7M 0.04% 490
2020
Q3
$28.4M Buy
+120,150
New +$27M 0.1% 212
2020
Q2
Sell
-75,156
Closed -$13.5M 3223
2020
Q1
$12.4M Sell
75,156
-86,880
-54% -$15.9M 0.1% 208
2019
Q4
$31.9M Buy
+162,036
New +$30.3M 0.1% 251
2018
Q4
Sell
-1,668
Closed -$319K 3236
2018
Q3
$319K Sell
1,668
-340,002
-100% -$60.4M ﹤0.01% 2733
2018
Q2
$54.5M Buy
341,670
+25,113
+8% +$3.83M 0.16% 162
2018
Q1
$43.6M Buy
316,557
+79,881
+34% +$11.1M 0.15% 179
2017
Q4
$28.8M Sell
236,676
-785,175
-77% -$98.3M 0.09% 284
2017
Q3
$119M Buy
1,021,851
+1,008,756
+7,703% +$110M 0.42% 50
2017
Q2
$1.36M Sell
13,095
-2,709
-17% -$260K ﹤0.01% 1702
2017
Q1
$1.35M Sell
15,804
-275,589
-95% -$21.8M ﹤0.01% 1723
2016
Q4
$20.5M Sell
291,393
-134,712
-32% -$9.9M 0.08% 302
2016
Q3
$34.3M Sell
426,105
-890,640
-68% -$68.2M 0.12% 182
2016
Q2
$96.8M Buy
1,316,745
+525,015
+66% +$36.9M 0.42% 45
2016
Q1
$52.9M Buy
791,730
+577,044
+269% +$35.8M 0.25% 93
2015
Q4
$13M Sell
214,686
-3,762
-2% -$211K 0.06% 344
2015
Q3
$11.2M Buy
218,448
+203,562
+1,367% +$11.5M 0.06% 339
2015
Q2
$801K Buy
14,886
+11,286
+314% +$631K ﹤0.01% 1814
2015
Q1
$202K Buy
+3,600
New +$204K ﹤0.01% 2488
2014
Q4
Sell
-414,459
Closed -$21.3M 2298
2014
Q3
$21.3M Buy
+414,459
New +$20.6M 0.1% 278
2014
Q2
Sell
-310,104
Closed -$15.1M 2244
2014
Q1
$15.1M Sell
310,104
-1,746,729
-85% -$82.3M 0.08% 330
2013
Q4
$87.8M Buy
2,056,833
+457,767
+29% +$19.3M 0.49% 29
2013
Q3
$66.9M Buy
1,599,066
+1,431,396
+854% +$63.2M 0.43% 57
2013
Q2
$9.44M Buy
+167,670
New +$9.24M 0.07% 357

Other funds holding ISRG

Two Sigma Investments's ISRG Position: Q1 2026 in Review

Two Sigma Investments increased its Intuitive Surgical (ISRG) stake by 206% in Q1 2026, buying an estimated $478M and bringing the position to 1,405,334 shares worth $648M. The position accounts for 0.52% of the portfolio, ranked #22.

Two Sigma Investments first reported a position in ISRG in Q2 2013 and has held it in 45 quarters since. 2,303 funds tracked by Wall St. Rank hold ISRG as of Q1 2026.

  • Two Sigma Investments held 1,405,334 shares of Intuitive Surgical worth $648M as of Q1 2026.
  • Two Sigma Investments bought 945,455 Intuitive Surgical shares in Q1 2026, an estimated $478M.
  • Intuitive Surgical made up 0.52% of Two Sigma Investments's portfolio in Q1 2026, its #22 holding.
  • Two Sigma Investments first reported a position in Intuitive Surgical in Q2 2013 and has held it in 45 quarters since.
  • 2,303 funds tracked by Wall St. Rank held Intuitive Surgical as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.